Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601852 | 0.81 | — | — | |
| SCHEMBL3971544 | 0.81 | ALOX5 (0.43) | ALOX5SPHK1ALDH1A1EPHX1TSHR | |
| SCHEMBL3971572 | 0.79 | GBA1 (0.45) | ALOX5SPHK1ALDH1A1EPHX1TSHR | |
| SCHEMBL416170 | 0.76 | ALOX5 (0.43) | ALOX5SPHK1ALDH1A1EPHX1TSHR | |
| SCHEMBL18657390 | 0.76 | ALOX5 (0.65) | ALOX5SPHK1ALDH1A1EPHX1TSHR | |
| SCHEMBL18685663 | 0.76 | ALOX5 (0.65) | ALOX5SPHK1ALDH1A1EPHX1TSHR | |
| SCHEMBL29971764 | 0.76 | ALOX5 (0.65) | ALOX5SPHK1ALDH1A1EPHX1TSHR | |
| SCHEMBL5241308 | 0.75 | ALOX5 (0.48) | ALOX5SPHK1ALDH1A1EPHX1TSHR | |
| SCHEMBL15155328 | 0.75 | ALOX5 (0.48) | ALOX5SPHK1ALDH1A1EPHX1TSHR | |
| SCHEMBL4272165 | 0.74 | ALOX5 (0.41) | ALOX5ALDH1A1EPHX1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790629-B1 | Derivatives of octahydro-cycloprop-indene and their use in perfume compositions | INT FLAVORS & FRAGRANCES INC (US) | 2013-07-03 | — | — | EP | disclosed |
| US-7482317-B2 | Derivatives of decahydro-cycloprop[e]indene compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-7482317-B2 | Derivatives of decahydro-cycloprop[e]indene compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-20070225200-A1 | DERIVATIVES OF DECAHYDRO-CYCLOPROP[E]INDENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-09-27 | — | — | US | disclosed |
| US-20070225200-A1 | DERIVATIVES OF DECAHYDRO-CYCLOPROP[E]INDENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-09-27 | — | — | US | disclosed |
| US-7232795-B2 | Derivatives of decahydro-cycloprop[e]indene compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-06-19 | — | — | US | disclosed |
| US-7232795-B2 | Derivatives of decahydro-cycloprop[e]indene compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-06-19 | — | — | US | disclosed |
| US-7232795-B2 | Derivatives of decahydro-cycloprop[e]indene compounds and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-06-19 | — | — | US | disclosed |
| EP-1790629-A1 | Derivatives of octahydro-cycloprop-indene and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2007-05-30 | — | — | EP | disclosed |
| EP-1790629-A1 | Derivatives of octahydro-cycloprop-indene and their use in perfume compositions | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2007-05-30 | — | — | EP | disclosed |
| US-20070117727-A1 | DERIVATIVES OF DECAHYDRO-CYCLOPROP[E]INDENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-05-24 | — | — | US | disclosed |
| US-20070117727-A1 | DERIVATIVES OF DECAHYDRO-CYCLOPROP[E]INDENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-05-24 | — | — | US | disclosed |
| US-20070117727-A1 | DERIVATIVES OF DECAHYDRO-CYCLOPROP[E]INDENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117727-A1 | DERIVATIVES OF DECAHYDRO-CYCLOPROP[E]INDENE COMPOUNDS AND THEIR USE IN PERFUME COMPOSITIONS | CPT1A, CYP8B1, DECR1 | ALOX5 156/4885SPHK1 1330/4885ALDH1A1 410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.