SCHEMBL3972450

SCHEMBL3972450

CN(OC(=O)O)OC(=O)O

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM6B O15054 1/20 0.36
KDM5C P41229 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
PHF8 Q9UPP1 1/20 0.36
KDM2A Q9Y2K7 1/20 0.36
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28325720 0.79
SCHEMBL28818985 0.76
SCHEMBL22201141 0.73
SCHEMBL8995960 0.71 ALDH1A1 (0.41) KDM6BKDM5CEGLN1PHF8KDM2A
Trimethylammonium SCHEMBL18173922 0.67
Trimethylammonium SCHEMBL874043 0.62 CA1 (0.56) KDM6BKDM5CEGLN1PHF8KDM2A
Trimethylammonium SCHEMBL28443711 0.62 CA1 (0.56) KDM6BKDM5CEGLN1PHF8KDM2A
Trimethylammonium SCHEMBL874044 0.62
Acetic Acid SCHEMBL9621249 0.59 FFAR3 (0.70) ALDH1A1TSHRFFAR3LCKFYN
Dimethylcarbate SCHEMBL1232328 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1654251-A4 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORP (US) 2009-03-11 EP disclosed
EP-1654251-A1 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2006-05-10 EP disclosed
WO-2005016914-A1 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2005-02-24 WO disclosed
US-5703260-A Process for the preparation of alkoxytriazolinones BAYER AKTIENGESELLSCHAFT (DE) 1997-12-30 US disclosed
US-5606070-A Process for the preparation of alkoxytriazolinones BAYER AKTIENGESELLSCHAFT (DE) 1997-02-25 US disclosed
US-5594147-A Process for the preparation of alkoxytriazolinones BAYER AKTIENGESELLSCHAFT (DE) 1997-01-14 US disclosed
US-5594148-A Process for the preparation of alkoxytriazolinones BAYER AKTIENGESELLSCHAFT (DE) 1997-01-14 US disclosed