Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 3/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.54 |
| ▸ | ANO1 | Q5XXA6 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974360 | 0.93 | PRKCZ (0.62) | PRKCZADORA1ANO1MEN1RAB9A | |
| SCHEMBL3976906 | 0.86 | PRKCZ (0.55) | PRKCZADORA1ANO1MEN1RAB9A | |
| SCHEMBL3974298 | 0.86 | PRKCZ (0.59) | PRKCZADORA1ANO1MEN1RAB9A | |
| SCHEMBL3976107 | 0.86 | PRKCZ (0.58) | PRKCZADORA1ANO1MEN1RAB9A | |
| SCHEMBL3976339 | 0.86 | PRKCZ (0.58) | PRKCZMEN1RAB9AKMT2APTGS1 | |
| SCHEMBL3972011 | 0.86 | PRKCZ (0.57) | PRKCZADORA1ANO1MEN1RAB9A | |
| SCHEMBL3980156 | 0.84 | PRKCZ (0.45) | PRKCZADORA1ANO1MEN1RAB9A | |
| SCHEMBL3975220 | 0.83 | PRKCZ (0.58) | PRKCZADORA1ANO1MEN1RAB9A | |
| SCHEMBL3976440 | 0.82 | PRKCZ (0.59) | PRKCZADORA1MEN1RAB9AKMT2A | |
| SCHEMBL3975200 | 0.80 | PRKCZ (0.48) | PRKCZADORA1MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | claimed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |