Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974360 | 0.88 | PRKCZ (0.62) | PRKCZMAPK1LMNAMAPTALDH1A1 | |
| SCHEMBL3979943 | 0.87 | PRKCZ (0.61) | PRKCZMAPK1POLBCA12CA1 | |
| SCHEMBL3974076 | 0.86 | MAPT (0.62) | PRKCZMAPK1LMNAMAPTALDH1A1 | |
| SCHEMBL3974298 | 0.82 | PRKCZ (0.59) | PRKCZMAPK1LMNAMAPTALDH1A1 | |
| SCHEMBL3976906 | 0.82 | PRKCZ (0.55) | PRKCZMAPK1LMNAMAPTALDH1A1 | |
| SCHEMBL3972589 | 0.82 | PRKCZ (0.55) | PRKCZMAPK1MAPTALDH1A1ADORA1 | |
| SCHEMBL3976107 | 0.81 | PRKCZ (0.58) | PRKCZMAPK1LMNAMAPTALDH1A1 | |
| SCHEMBL3972011 | 0.81 | PRKCZ (0.57) | PRKCZMAPK1POLBLMNAMAPT | |
| SCHEMBL4963547 | 0.81 | PRKCZ (0.67) | PRKCZMAPK1LMNAGAAMAPT | |
| SCHEMBL3975220 | 0.79 | PRKCZ (0.58) | PRKCZMAPK1POLBLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |
| WO-2009049362-A1 | A1 ADENOSINE RECEPTOR ALLOSTERIC ENHANCERS | MONASH UNIVERSITY (AU) | 2009-04-23 | — | — | WO | disclosed |