Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762577 | 0.83 | TAS2R38 (0.42) | TSHRSMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL8256708 | 0.81 | TSHR (0.47) | TSHRACHESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL1029641 | 0.79 | HPGD (0.47) | TSHRACHESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL31135508 | 0.79 | HPGD (0.47) | TSHRACHESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL39369 | 0.78 | TSHR (0.50) | TSHRACHESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL2451836 | 0.78 | TSHR (0.50) | TSHRACHESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7346004 | 0.77 | TSHR (0.43) | TSHRACHESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL5426379 | 0.77 | TSHR (0.43) | TSHRACHESMN1; SMN2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL10333053 | 0.77 | MAOA (0.47) | TSHRACHESMN1; SMN2ALDH1A1POLB | |
| SCHEMBL7442372 | 0.77 | TSHR (0.43) | TSHRACHESMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110914241-B | Propionic acid derivatives and methods of use thereof | 阿维亚拉药品有限公司 | 2023-11-14 | — | — | CN | disclosed |
| US-7566737-B2 | Combinations of substituted 1,3-diphenylprop-2-en-1-one derivatives with other therapeutically active ingredients | GENFIT (FR) | 2009-07-28 | — | — | US | disclosed |
| US-20070032543-A1 | Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients | GENFIT (FR) | 2007-02-08 | — | — | US | disclosed |
| EP-0019450-B1 | PYRIMIDINE DERIVATIVES AND THEIR PRODUCTION AND AGRICULTURAL USES | Takeda Chemical Industries, Ltd. (JP) | 1983-02-23 | — | — | EP | disclosed |
| EP-0019450-A1 | Pyrimidine derivatives and their production and agricultural uses | Takeda Chemical Industries, Ltd. (JP) | 1980-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032543-A1 | Combinations of substituted 1,3-diphenylprop-2-EN-1-one derivatives with other therapeutically active ingredients | PSEN1, BACE1, PSEN2 | TSHR 4430/4885ACHE 472/4885SMN1; SMN2 113/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.