Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 3/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154857 | 0.93 | CYP4A11 (0.50) | CYP4A11CYP4F2PPARACA2CA1 | |
| SCHEMBL9808692 | 0.88 | TAAR1 (0.45) | CA2CA1CA12CA4CA6 | |
| SCHEMBL9808660 | 0.85 | ESR1 (0.45) | CYP4A11CYP4F2ESRRG | |
| SCHEMBL3687860 | 0.84 | PLK1 (0.41) | CYP4A11CA2ESRRG | |
| SCHEMBL9808693 | 0.83 | CYP4A11 (0.57) | CYP4A11CYP4F2PPARACA2ESRRG | |
| SCHEMBL28584026 | 0.79 | CYP4A11 (0.47) | CYP4A11CYP4F2PPARACA2CA1 | |
| SCHEMBL1060928 | 0.79 | PLK1 (0.55) | TDP1 | |
| SCHEMBL480503 | 0.78 | EPHX2 (0.49) | PPARACA2CA1CA12CA4 | |
| SCHEMBL3976669 | 0.77 | KMT2A (0.47) | CYP4A11ESRRGTDP1 | |
| SCHEMBL153898 | 0.76 | KMT2A (0.56) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367743-B2 | Adhesion promoting photoinitiators for UV cured coatings over metal surfaces | BASF SE (DE) | 2013-02-05 | — | — | US | disclosed |
| US-20090104464-A1 | Adhesion promoting photoinitiators for UV cured coatings over metal surfaces | IGM GROUP B.V. (NL) | 2009-04-23 | — | — | US | disclosed |
| WO-2009050116-A2 | ADHESION PROMOTING PHOTOINITIATORS FOR UV CURED COATINGS OVER METAL SURFACES | BASF SE (DE) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090104464-A1 | Adhesion promoting photoinitiators for UV cured coatings over metal surfaces | CDH1, PCNA, VCAM1 | CYP4A11 4662/4885CYP4F2 3785/4885PPARA 1249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.