Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5137788 | 0.99 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL5661987 | 0.84 | DGAT1 (0.36) | DGAT1NPC1MAPT | |
| SCHEMBL1858968 | 0.82 | DGAT1 (0.38) | DGAT1MAPT | |
| SCHEMBL7082758 | 0.81 | DGAT1 (0.34) | DGAT1NPC1MAPT | |
| SCHEMBL3973414 | 0.81 | SMN1; SMN2 (0.35) | DGAT1NPC1MAPT | |
| SCHEMBL3313603 | 0.80 | NPC1 (0.40) | DGAT1NPC1MAPT | |
| SCHEMBL8664242 | 0.80 | DGAT1 (0.34) | DGAT1NPC1MAPT | |
| SCHEMBL26917090 | 0.79 | DGAT1 (0.35) | DGAT1NPC1MAPT | |
| SCHEMBL31305763 | 0.78 | SMN1; SMN2 (0.33) | DGAT1NPC1MAPT | |
| SCHEMBL6171967 | 0.78 | DGAT1 (0.34) | DGAT1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2016057-A1 | C-FMS KINASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-01-21 | — | — | EP | disclosed |
| WO-2007123516-A1 | C-FMS KINASE INHIBITORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-11-01 | — | — | WO | disclosed |