Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29753992 | 0.84 | PTGS2 (0.52) | MAPK1KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL3018679 | 0.84 | PTGS2 (0.52) | MAPK1KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL3982461 | 0.83 | CYP3A4 (0.43) | MAPK1KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL8380237 | 0.82 | PTGS2 (0.50) | MAPK1KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL8380233 | 0.82 | PTGS2 (0.50) | MAPK1KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL2046110 | 0.82 | ELANE (0.39) | MAPK1KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL10499975 | 0.81 | MAPK1 (0.42) | MAPK1KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL19141078 | 0.81 | TTR (0.50) | MAPK1KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL5212814 | 0.81 | MAPK1 (0.71) | MAPK1KDM4EALDH1A1BLMTDP1 | |
| SCHEMBL10351036 | 0.77 | MAPK1 (0.61) | MAPK1KDM4EALDH1A1BLMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2056805-A1 | USE OF 2, 5-DIHYDROXYBENZENE DERIVATIVES FOR THE TREATMENT OF TISSUE REACTIVE DISEASES | Action Medicines, S.L. (ES) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008020042-A1 | USE OF 2, 5-DIHYDROXYBENZENE DERIVATIVES FOR THE TREATMENT OF TISSUE REACTIVE DISEASES | ACTION MEDICINES, S.L. (ES) | 2008-02-21 | — | — | WO | disclosed |