Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21191549 | 0.81 | PDE4A (0.34) | CCR2TSHRPDE4APDE4BPDE4C | |
| SCHEMBL22023911 | 0.77 | SLC2A1 (0.35) | TSHRPDE4A | |
| SCHEMBL22024008 | 0.75 | CCR2 (0.36) | CCR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23634129 | 0.75 | CCR2 (0.36) | CCR2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14592820 | 0.72 | ALDH1A1 (0.34) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8931418 | 0.72 | ALDH1A1 (0.34) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14592897 | 0.72 | ALDH1A1 (0.34) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28051920 | 0.69 | — | — | |
| SCHEMBL20745972 | 0.69 | PDE4A (0.31) | TSHRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12507526 | 0.69 | PDE4A (0.31) | TSHRPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053446-A2 | PREGABALIN INTERMEDIATES AND PROCESS FOR PREPARING THEM AND PREGABALIN | CHEMO IBÉRICA, S.A. (ES) | 2009-04-30 | — | — | WO | claimed |
| WO-2009053446-A2 | PREGABALIN INTERMEDIATES AND PROCESS FOR PREPARING THEM AND PREGABALIN | CHEMO IBÉRICA, S.A. (ES) | 2009-04-30 | — | — | WO | disclosed |