SCHEMBL3974367

SCHEMBL3974367

CCCCCCCCCC(=O)NN1CCCCC1

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 1/20 0.69
GNAO1 P09471 1/20 0.69
GNAI1 P63096 1/20 0.69
CNR1 P21554 4/20 0.57
CNR2 P34972 3/20 0.57
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
TDP1 Q9NUW8 1/20 0.53
FAAH O00519 4/20 0.50
MAPK1 P28482 1/20 0.50
HSP90AA1 P07900 1/20 0.50
ALDH1A1 P00352 2/20 0.46
TRPV1 Q8NER1 4/20 0.45
MAPT P10636 1/20 0.44
UGCG Q16739 2/20 0.44
NAAA Q02083 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3868277 1.00 GNAI3 (0.69) GNAI3GNAO1GNAI1CNR1CNR2
SCHEMBL16010753 1.00 GNAI3 (0.69) GNAI3GNAO1GNAI1CNR1CNR2
SCHEMBL11215579 0.98 GNAI3 (0.71) GNAI3GNAO1GNAI1CNR1CNR2
SCHEMBL8588178 0.98 GNAI3 (0.71) GNAI3GNAO1GNAI1CNR1CNR2
SCHEMBL3871463 0.98 GNAI3 (0.71) GNAI3GNAO1GNAI1CNR1CNR2
SCHEMBL2364796 0.93 GNAI3 (0.58) GNAI3GNAO1GNAI1CNR1CNR2
SCHEMBL16405435 0.91 GNAI3 (0.60) GNAI3GNAO1GNAI1CNR1CNR2
SCHEMBL3855059 0.88 GNAI3 (0.55) GNAI3GNAO1GNAI1CNR1CNR2
SCHEMBL3848549 0.86 GNAI3 (0.56) GNAI3GNAO1GNAI1CNR1CNR2
SCHEMBL493880 0.85 TP53 (0.50) GNAI3GNAO1GNAI1CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9000190-B2 Amide compound or salt thereof, biofilm inhibitor, biofilm remover and disinfectant containing the same UNIVERSITY OF TOKYO (JP) 2015-04-07 US disclosed
EP-2077260-B1 AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM FORMATION INHIBITOR, BIOFILM REMOVER AND BACTERICIDE EACH USING THE AMIDE COMPOUND OR SALT THEREOF UNIV TOKYO (JP) 2015-02-18 EP disclosed
US-20150018564-A1 AMIDE COMPOUND OR SALT THEREOF, BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME UNIVERSITY OF TOKYO (JP) 2015-01-15 US disclosed
US-8748617-B2 Amide compound or salt thereof, and biofilm inhibitor, biofilm remover and disinfectant containing the same UNIVERSITY OF TOKYO (JP) 2014-06-10 US disclosed
US-20120296094-A1 AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME OTSUKA CHEMICAL CO., LTD. (JP) 2012-11-22 US disclosed
US-8258307-B2 Amide compound or salt thereof, and biofilm inhibitor, biofilm remover and disinfectant containing the same UNIVERSITY OF TOKYO (JP) 2012-09-04 US disclosed
EP-2077260-A1 AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM FORMATION INHIBITOR, BIOFILM REMOVER AND BACTERICIDE EACH USING THE AMIDE COMPOUND OR SALT THEREOF The University of Tokyo (JP) 2009-07-08 EP disclosed
US-20090068120-A1 AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME OTSUKA CHEMICAL CO., LTD. (JP) 2009-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150018564-A1 AMIDE COMPOUND OR SALT THEREOF, BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME Q6ZSR9, F12, H1-0 GNAI3 2508/4885GNAO1 2462/4885GNAI1 1061/4885
US-20090068120-A1 AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME Q6ZSR9, F12, H1-0 GNAI3 2369/4885GNAO1 2572/4885GNAI1 1109/4885
US-20120296094-A1 AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME Q6ZSR9, F12, H1-0 GNAI3 2369/4885GNAO1 2572/4885GNAI1 1109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.