Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364252 | 1.00 | TP53 (0.50) | TP53NPC1RAB9ASMN1; SMN2GNAI3 | |
| SCHEMBL3879759 | 0.98 | GNAI3 (0.50) | TP53NPC1RAB9ASMN1; SMN2GNAI3 | |
| SCHEMBL2364796 | 0.88 | GNAI3 (0.58) | TP53NPC1RAB9ASMN1; SMN2GNAI3 | |
| SCHEMBL16405435 | 0.86 | GNAI3 (0.60) | GNAI3GNAO1GNAI1CNR2CNR1 | |
| SCHEMBL16010753 | 0.85 | GNAI3 (0.69) | GNAI3GNAO1GNAI1CNR2CNR1 | |
| SCHEMBL3868277 | 0.85 | GNAI3 (0.69) | GNAI3GNAO1GNAI1CNR2CNR1 | |
| SCHEMBL3974367 | 0.85 | GNAI3 (0.69) | GNAI3GNAO1GNAI1CNR2CNR1 | |
| SCHEMBL28996573 | 0.83 | CA12 (0.46) | TP53NPC1RAB9ASMN1; SMN2GNAI3 | |
| SCHEMBL4591725 | 0.83 | HTT (0.47) | TP53SMN1; SMN2GNAI3GNAO1GNAI1 | |
| SCHEMBL3871463 | 0.82 | GNAI3 (0.71) | GNAI3GNAO1GNAI1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110090303-A | Opioid receptor agonist is manufacturing the purposes in the drug for treating malignant tumour | 浙江大学 | 2019-08-06 | — | — | CN | disclosed |
| US-9000190-B2 | Amide compound or salt thereof, biofilm inhibitor, biofilm remover and disinfectant containing the same | UNIVERSITY OF TOKYO (JP) | 2015-04-07 | — | — | US | disclosed |
| US-9000190-B2 | Amide compound or salt thereof, biofilm inhibitor, biofilm remover and disinfectant containing the same | UNIVERSITY OF TOKYO (JP) | 2015-04-07 | — | — | US | disclosed |
| US-20150018564-A1 | AMIDE COMPOUND OR SALT THEREOF, BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME | UNIVERSITY OF TOKYO (JP) | 2015-01-15 | — | — | US | disclosed |
| US-20150018564-A1 | AMIDE COMPOUND OR SALT THEREOF, BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME | UNIVERSITY OF TOKYO (JP) | 2015-01-15 | — | — | US | disclosed |
| US-8748617-B2 | Amide compound or salt thereof, and biofilm inhibitor, biofilm remover and disinfectant containing the same | UNIVERSITY OF TOKYO (JP) | 2014-06-10 | — | — | US | disclosed |
| US-8748617-B2 | Amide compound or salt thereof, and biofilm inhibitor, biofilm remover and disinfectant containing the same | UNIVERSITY OF TOKYO (JP) | 2014-06-10 | — | — | US | disclosed |
| EP-1940845-B1 | NOVEL AZETIDINE COMPOUNDS USEFUL IN THE TREATMENT OF FUNCTIONAL GASTROINTESTINAL DISORDERS, IBS AND FUNCTIONAL DYSPEPSIA | ALBIREO AB (SE) | 2013-06-12 | — | — | EP | disclosed |
| EP-2533645-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | The Johns Hopkins University (US) | 2012-12-19 | — | — | EP | disclosed |
| US-20120296094-A1 | AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME | OTSUKA CHEMICAL CO., LTD. (JP) | 2012-11-22 | — | — | US | disclosed |
| EP-1789389-A1 | PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2007-05-30 | — | — | EP | disclosed |
| WO-2007037743-A1 | NOVEL AZETIDINE COMPOUNDS USEFUL IN THE TREATMENT OF FUNCTIONAL GASTROINTESTINAL DISORDERS, IBS AND FUNCTIONAL DYSPEPSIA | ASTRAZENECA AB (SE) | 2007-04-05 | — | — | WO | disclosed |
| WO-2007037742-A1 | NOVEL AZETIDINE COMPOUNDS USEFUL IN THE TREATMENT OF FUNCTIONAL GASTROINTESTINAL DISORDERS, IBS AND FUNCTIONAL DYSPEPSIA | ASTRAZENECA AB (SE) | 2007-04-05 | — | — | WO | disclosed |
| WO-2006137790-A1 | NEW AZETIDINE DERIVATIVES AS NEUROKININ RECEPTOR ANTAGONISTS FOR THE TREATMENT OF GASTROINTESTINAL DISEASES | ASTRAZENECA AB (SE) | 2006-12-28 | — | — | WO | disclosed |
| WO-2006137791-A1 | NEW AZETIDINE DERIVATIVES AS NEUROKININ RECEPTOR ANTAGONISTS FOR THE TREATMENT OF GASTROINTESTINAL DISEASES | ASTRAZENECA AB (SE) | 2006-12-28 | — | — | WO | disclosed |
| US-20060172988-A1 | Azetidine compounds | ALBIREO AB (SE) | 2006-08-03 | — | — | US | disclosed |
| CN-1805957-A | Azetidine compounds | ASTRAZENECA AB (SE) | 2006-07-19 | — | — | CN | disclosed |
| WO-2006030984-A1 | PIPERIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2006-03-23 | — | — | WO | disclosed |
| EP-1636221-A2 | NEW AZETIDINE COMPOUNDS | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110344-A2 | NEW AZETIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150018564-A1 | AMIDE COMPOUND OR SALT THEREOF, BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME | Q6ZSR9, F12, H1-0 | TP53 3302/4885NPC1 2670/4885RAB9A 524/4885 |
| US-20120296094-A1 | AMIDE COMPOUND OR SALT THEREOF, AND BIOFILM INHIBITOR, BIOFILM REMOVER AND DISINFECTANT CONTAINING THE SAME | Q6ZSR9, F12, H1-0 | TP53 3126/4885NPC1 2900/4885RAB9A 458/4885 |
| US-20060172988-A1 | Azetidine compounds | HRH2, HRH4, HRH1 | TP53 3921/4885NPC1 457/4885RAB9A 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.