Glutamine

Glutamine

SCHEMBL3974526

CC[C@H](C)[C@H](N)C(=O)O.C[C@H](NC1CCCCC1)C(=O)O.NC(=O)CC[C@H](N)C(=O)O

nearest known ligand 0.43

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.43
ALOX15 P16050 1/20 0.43
BLM P54132 1/20 0.43
PMP22 Q01453 1/20 0.43
DPP4 P27487 8/20 0.36
DPP8 Q6V1X1 5/20 0.36
DPP9 Q86TI2 3/20 0.36
DPP7 Q9UHL4 3/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
EPHX1 P07099 1/20 0.33
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
RECQL P46063 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
EPHX2 P34913 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GRM8 O00222 1/20 0.32
GRM6 O15303 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoleucine SCHEMBL7419038 0.88 EPHX1 (0.41) KMT2ADPP4DPP8DPP9DPP7
Isoleucine SCHEMBL7419039 0.88 EPHX1 (0.41) KMT2ADPP4DPP8DPP9DPP7
Glutamine SCHEMBL3974114 0.86 BLM (0.47) KMT2AALOX15BLMPMP22DPP4
Glutamine SCHEMBL3980215 0.83 KMT2A (0.44) KMT2AALOX15BLMPMP22DPP4
D-Glutamate SCHEMBL4777197 0.81 CYP1A2 (0.51) KMT2AALOX15BLMPMP22DPP4
Glutamic Acid SCHEMBL3738402 0.81 CYP1A2 (0.51) KMT2AALOX15BLMPMP22DPP4
Arginine SCHEMBL27539177 0.81 OTC (0.32) DPP4DPP8DPP9DPP7SMN1; SMN2
Glutamine SCHEMBL1537391 0.81 KMT2A (0.66) KMT2AALOX15BLMPMP22DPP4
Glutamine SCHEMBL1537469 0.81 KMT2A (0.66) KMT2AALOX15BLMPMP22DPP4
Glutamine SCHEMBL1446882 0.81 KMT2A (0.66) KMT2AALOX15BLMPMP22DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1474439-B1 DIPEPTIDES AND TRIPEPTIDES WITH ANTI-INFLAMMATORY ACTIVITY SALPEP BIOTECHNOLOGY INC (CA) 2009-05-06 EP claimed