Glutamic Acid

Glutamic Acid

SCHEMBL3738402

C[C@H](NC1CCCCC1)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.51
GRM8 O00222 1/20 0.51
GRM6 O15303 1/20 0.51
GRIN2D O15399 1/20 0.51
GRIN3B O60391 1/20 0.51
GSR P00390 1/20 0.51
GRIK1 P39086 1/20 0.51
GRM5 P41594 1/20 0.51
GRIA1 P42261 1/20 0.51
GRIA2 P42262 1/20 0.51
GRIA3 P42263 1/20 0.51
SLC1A3 P43003 1/20 0.51
SLC1A2 P43004 1/20 0.51
SLC1A1 P43005 1/20 0.51
GRIA4 P48058 1/20 0.51
GRIN1 Q05586 1/20 0.51
GRIN2A Q12879 1/20 0.51
GRIK2 Q13002 1/20 0.51
GRIK3 Q13003 1/20 0.51
GRIN2B Q13224 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL4777197 1.00 CYP1A2 (0.51) CYP1A2GRM8GRM6GRIN2DGRIN3B
Glutamic Acid SCHEMBL3974519 0.91 LMNA (0.43) CYP1A2GRM8GRM6GRIN2DGRIN3B
Glutamine SCHEMBL3974114 0.88 BLM (0.47) CYP1A2GRM8GRM6GRIN2DGRIN3B
Beta-Alanine SCHEMBL3503929 0.84 ALDH1A1 (0.44) CYP1A2LMNAALDH1A1SMN1; SMN2KMT2A
Lysine SCHEMBL237659 0.83 GSR (0.54) GSRDPP4DPP8DPP9FAP
Lysine SCHEMBL237658 0.83 GSR (0.54) GSRDPP4DPP8DPP9FAP
Glutamic Acid SCHEMBL27975498 0.83 GRM8 (0.60) CYP1A2GRM8GRM6GRIN2DGRIN3B
D-Glutamate SCHEMBL27975473 0.83 GRM8 (0.60) CYP1A2GRM8GRM6GRIN2DGRIN3B
Glutamine SCHEMBL3980215 0.82 KMT2A (0.44) CYP1A2GRM8GRM6GRIN2DGRIN3B
Leucine SCHEMBL6369626 0.82 SLC7A5 (0.55) GRIK1SLC1A3SLC1A2SLC1A1GRIK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100279944-A1 SUPPRESSION AND TREATMENT OF NEUROPATHIC PAIN MATHISON RONALD 2010-11-04 US claimed
EP-2072524-A2 Anti-inflammatory peptides Salpep Biotechnology, Inc. (CA) 2009-06-24 EP claimed
EP-1998791-A1 SUPPRESSION AND TREATMENT OF NEUROPATHIC PAIN Salpep Biotechnology, Inc. (CA) 2008-12-10 EP claimed
WO-2007112556-A1 SUPPRESSION AND TREATMENT OF NEUROPATHIC PAIN SALPEP BIOTECHNOLOGY INC. (CA) 2007-10-11 WO claimed
US-20070054865-A1 Anti-inflammatory peptides AIM THERAPEUTICS INC. (CA) 2007-03-08 US claimed
EP-1474439-A2 DIPEPTIDES AND TRIPEPTIDES WITH ANTI-INFLAMMATORY ACTIVITY Salpep Biotechnology Inc. (CA) 2004-11-10 EP claimed
US-20030195141-A1 Anti-inflammatory peptides AIM THERAPEUTICS INC. (CA) 2003-10-16 US claimed
WO-2003066670-A2 DIPEPTIDES AND TRIPEPTIDES WITH ANTI-INFLAMMATORY ACTIVITY SALPEP BIOTECHNOLOGY INC. (CA) 2003-08-14 WO claimed
US-20100279944-A1 SUPPRESSION AND TREATMENT OF NEUROPATHIC PAIN MATHISON RONALD 2010-11-04 US disclosed
EP-2072524-A2 Anti-inflammatory peptides Salpep Biotechnology, Inc. (CA) 2009-06-24 EP disclosed
EP-1998791-A1 SUPPRESSION AND TREATMENT OF NEUROPATHIC PAIN Salpep Biotechnology, Inc. (CA) 2008-12-10 EP disclosed
WO-2007112556-A1 SUPPRESSION AND TREATMENT OF NEUROPATHIC PAIN SALPEP BIOTECHNOLOGY INC. (CA) 2007-10-11 WO disclosed