Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | GRM8 | O00222 | 1/20 | 0.51 |
| ▸ | GRM6 | O15303 | 1/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GSR | P00390 | 1/20 | 0.51 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.51 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.51 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.51 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutamic Acid SCHEMBL3738402 | 1.00 | CYP1A2 (0.51) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| Glutamic Acid SCHEMBL3974519 | 0.91 | LMNA (0.43) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| Glutamine SCHEMBL3974114 | 0.88 | BLM (0.47) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| Beta-Alanine SCHEMBL3503929 | 0.84 | ALDH1A1 (0.44) | CYP1A2LMNAALDH1A1SMN1; SMN2KMT2A | |
| Lysine SCHEMBL237659 | 0.83 | GSR (0.54) | GSRDPP4DPP8DPP9FAP | |
| Lysine SCHEMBL237658 | 0.83 | GSR (0.54) | GSRDPP4DPP8DPP9FAP | |
| Glutamic Acid SCHEMBL27975498 | 0.83 | GRM8 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| D-Glutamate SCHEMBL27975473 | 0.83 | GRM8 (0.60) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| Glutamine SCHEMBL3980215 | 0.82 | KMT2A (0.44) | CYP1A2GRM8GRM6GRIN2DGRIN3B | |
| Leucine SCHEMBL6369626 | 0.82 | SLC7A5 (0.55) | GRIK1SLC1A3SLC1A2SLC1A1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1998791-A1 | SUPPRESSION AND TREATMENT OF NEUROPATHIC PAIN | Salpep Biotechnology, Inc. (CA) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007112556-A1 | SUPPRESSION AND TREATMENT OF NEUROPATHIC PAIN | SALPEP BIOTECHNOLOGY INC. (CA) | 2007-10-11 | — | — | WO | disclosed |