Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 7/20 | 0.70 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 5/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 3/20 | 0.52 |
| ▸ | CASP7 | P55210 | 3/20 | 0.52 |
| ▸ | HBB | P68871 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PRNP | P04156 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980449 | 0.92 | SLC2A1 (0.78) | FLT3SLC2A1POLBRAD52TP53 | |
| SCHEMBL6670648 | 0.89 | SLC2A1 (0.80) | FLT3SLC2A1POLBRAD52RXFP1 | |
| SCHEMBL3972870 | 0.87 | SLC2A1 (0.70) | FLT3SLC2A1POLBRAD52MEN1 | |
| SCHEMBL17897969 | 0.83 | FLT3 (1.00) | FLT3 | |
| SCHEMBL3973291 | 0.83 | SLC2A1 (0.64) | FLT3SLC2A1POLBRAD52MEN1 | |
| SCHEMBL6671471 | 0.83 | SLC2A1 (0.70) | FLT3SLC2A1POLBRAD52TP53 | |
| SCHEMBL3972522 | 0.82 | SLC2A1 (0.63) | FLT3SLC2A1POLBTP53MEN1 | |
| SCHEMBL3978534 | 0.81 | FLT3 (0.59) | FLT3SLC2A1POLBUSP2TP53 | |
| SCHEMBL3976619 | 0.80 | SLC2A1 (0.64) | FLT3SLC2A1POLBRAD52HSD17B10 | |
| SCHEMBL3973379 | 0.80 | SLC2A1 (0.64) | FLT3SLC2A1POLBRAD52HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7547702-B2 | 4-amino-quinazolines | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-20060019974-A1 | Glycoprotein antagonist; anticholesterol agents; cardiovascular disorders; strokes; antiischemic agents | ORTHO-MCNEIL PHARMACEUTICALS, INC. | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019974-A1 | Glycoprotein antagonist; anticholesterol agents; cardiovascular disorders; strokes; antiischemic agents | SERPINA3, APOL1, MGAT3 | FLT3 1822/4885SLC2A1 1107/4885POLB 4723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.