Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 4/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4990505 | 0.66 | PIM3 (0.47) | — | |
| SCHEMBL11150107 | 0.64 | NOS1 (0.41) | DAOTDO2IDO1NOS1GRIN2B | |
| SCHEMBL24392413 | 0.61 | KDM4E (0.53) | GRIN2B | |
| SCHEMBL29588761 | 0.61 | KDM4E (0.53) | GRIN2B | |
| SCHEMBL30095611 | 0.60 | JAK2 (0.41) | IDO1JAK2JAK1TYK2JAK3 | |
| SCHEMBL30822495 | 0.60 | PTPN6 (0.39) | TDO2IDO1NOS1GSK3BPIK3CD | |
| SCHEMBL16636860 | 0.60 | PTPN6 (0.39) | TDO2IDO1NOS1GSK3BPIK3CD | |
| SCHEMBL17030860 | 0.60 | GRIN2D (0.50) | TDO2IDO1NOS1GRIN2BJAK2 | |
| SCHEMBL7883156 | 0.59 | PDE9A (0.49) | — | |
| SCHEMBL12018677 | 0.59 | MAPK10 (0.47) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009053799-A1 | NOVEL CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS, S.A. (US) | 2009-04-30 | — | — | WO | disclosed |