Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM3 | Q86V86 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3532098 | 0.76 | CHEK1 (0.50) | PIM3MAPK10RIPK1 | |
| SCHEMBL11150107 | 0.71 | NOS1 (0.41) | — | |
| SCHEMBL239399 | 0.70 | ALDH1A1 (0.49) | NPC1MTOR | |
| SCHEMBL9425210 | 0.67 | ALDH1A1 (0.49) | NPC1 | |
| SCHEMBL24392413 | 0.67 | KDM4E (0.53) | MAPK10RIPK1 | |
| SCHEMBL29588761 | 0.67 | KDM4E (0.53) | MAPK10RIPK1 | |
| SCHEMBL3974738 | 0.66 | DAO (0.33) | — | |
| SCHEMBL9182150 | 0.66 | NPC1 (0.49) | NPC1MTOR | |
| SCHEMBL11433959 | 0.66 | KDM4E (0.51) | NPC1MTOR | |
| SCHEMBL17030860 | 0.66 | GRIN2D (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260033494-A1 | PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF | TEXAS A & M UNIV SYS (US) | 2026-02-05 | — | — | US | disclosed |
| US-7468366-B2 | Cytotoxic agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2008-12-23 | — | — | US | disclosed |
| EP-1453812-B1 | CYTOTOXIC AGENTS | UNIV RUTGERS (US) | 2008-08-20 | — | — | EP | disclosed |
| US-20080090831-A1 | CYTOTOXIC AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2008-04-17 | — | — | US | disclosed |
| US-7319105-B2 | Methylenedioxy-fused heterocycles, especially 8,10-dioxa-4,5,6,12-tetraaza-cyclopenta[b]chrysen-13-ones; 8,10-dioxa-1,4,5,6,12-pentaaza-cyclopenta[b]chrysen-13-ones; 8,10,12-trioxa-5,6-diaza-cyclopenta[b]chrysenes; and 8,10,12-trioxa-6-aza-cyclopenta[b]chrysenes; topoisomerase inhibitors; treating cancer | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2008-01-15 | — | — | US | disclosed |
| US-20050009825-A1 | Cytotoxic agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2005-01-13 | — | — | US | disclosed |
| EP-1453812-A2 | CYTOTOXIC AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003041653-A2 | CYTOTOXIC AGENTS | RUTGERS, THE STATE UNIVERSITY (US) | 2003-05-22 | — | — | WO | disclosed |
| US-4495351-A | FOR UROGENVITAL DISORDERS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1985-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260033494-A1 | PLANT ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF | MYB, DDT, PDE1C | PIM3 2103/4885MAPK10 2135/4885RIPK1 2368/4885 |
| US-20050009825-A1 | Cytotoxic agents | TOP1, TOP2A, TOP2B | PIM3 1954/4885MAPK10 3976/4885RIPK1 3643/4885 |
| US-20080090831-A1 | CYTOTOXIC AGENTS | TOP1, TOP2A, TOP2B | PIM3 1954/4885MAPK10 3976/4885RIPK1 3643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.