Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020205 | 0.89 | CYP1A2 (0.43) | CYP1A2HIF1AKDM4EHSD17B10SLC6A2 | |
| SCHEMBL7718731 | 0.89 | CYP1A2 (0.43) | CYP1A2HIF1AKDM4EHSD17B10SLC6A2 | |
| SCHEMBL8020201 | 0.89 | CYP1A2 (0.43) | CYP1A2HIF1AKDM4EHSD17B10SLC6A2 | |
| SCHEMBL29127898 | 0.81 | ALDH1A1 (0.44) | CYP1A2HIF1AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL7669472 | 0.81 | SLC6A2 (0.38) | CYP1A2HIF1AKDM4EHSD17B10SLC6A2 | |
| SCHEMBL19104463 | 0.81 | ALDH1A1 (0.44) | CYP1A2HIF1AKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL15903376 | 0.80 | SLC6A2 (0.37) | CYP1A2HIF1AKDM4EHSD17B10SLC6A2 | |
| SCHEMBL11069475 | 0.80 | CHRM2 (0.40) | CYP1A2HIF1ASLC6A2SLC6A4CHRM2 | |
| SCHEMBL7199227 | 0.79 | CYP1A2 (0.42) | CYP1A2HIF1AKDM4EHSD17B10CHRM2 | |
| SCHEMBL8999987 | 0.78 | CYP1A2 (0.45) | CYP1A2HIF1AKDM4EHSD17B10CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049018-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |