Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.69 |
| ▸ | CA4 | P22748 | 2/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | CA12 | O43570 | 1/20 | 0.69 |
| ▸ | CA1 | P00915 | 1/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | CA3 | P07451 | 1/20 | 0.69 |
| ▸ | CA9 | Q16790 | 1/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.69 |
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL28144641 | 1.00 | CA2 (0.69) | CA2CA4TDP1CA12CA1 | |
| Phenol SCHEMBL28395178 | 1.00 | CA2 (0.69) | CA2CA4TDP1CA12CA1 | |
| Phenol SCHEMBL4249298 | 1.00 | CA2 (0.69) | CA2CA4TDP1CA12CA1 | |
| Phenol SCHEMBL28109432 | 1.00 | CA2 (0.69) | CA2CA4TDP1CA12CA1 | |
| Phenol SCHEMBL131695 | 1.00 | CA2 (0.69) | CA2CA4TDP1CA12CA1 | |
| Phenol SCHEMBL20139217 | 1.00 | CA2 (0.69) | CA2CA4TDP1CA12CA1 | |
| Phenol SCHEMBL18045508 | 1.00 | CA2 (0.69) | CA2CA4TDP1CA12CA1 | |
| Phenol SCHEMBL20264 | 1.00 | CA2 (0.69) | CA2CA4TDP1CA12CA1 | |
| Phenol SCHEMBL28873525 | 1.00 | CA2 (0.69) | CA2CA4TDP1CA12CA1 | |
| Phenol SCHEMBL4857618 | 1.00 | CA2 (0.69) | CA2CA4TDP1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689783-A | The multifunctional flame-proof thermoplastic compounds of personal safety equipment for connection | 沙特基础工业全球技术公司 | 2019-04-26 | — | — | CN | claimed |
| CN-108504073-A | A kind of PC materials being useful in laptop | 何平 | 2018-09-07 | — | — | CN | claimed |
| CN-101031577-A | Poly (arylene ether) composition | GEN ELECTRIC (US) | 2007-09-05 | — | — | CN | claimed |
| CN-110191908-A | High flow polyetherimide compositions and articles made therefrom | 沙特基础工业全球技术有限公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-110105020-A | A kind of clear-water concrete and preparation method thereof | 梁剑 | 2019-08-09 | — | — | CN | disclosed |
| CN-106211777-B | The seven phosphorus derivative compounds as fire retardant | 巴斯夫欧洲公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-109721291-A | A kind of corrosion-resistant fire-proof wall material | 天津华安天建门业有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-104744587-B | Single chain FC polypeptides | UCB医药有限公司 | 2019-01-11 | — | — | CN | disclosed |
| CN-105849192-B | Reinforced flame retardant polycarbonate compositions and molded articles comprising the same | 沙特基础工业全球技术公司 | 2018-11-06 | — | — | CN | disclosed |
| CN-108504063-A | Halogen-free flame retardant PC/CF composite materials and products thereof | 汉达精密电子(昆山)有限公司 | 2018-09-07 | — | — | CN | disclosed |
| CN-106283265-B | A kind of preparation method of the microcosmic finely dispersed fire-retardant spandex of basic zirconium phosphate synergistic | 浙江华峰氨纶股份有限公司 | 2018-06-26 | — | — | CN | disclosed |
| CN-107001857-A | High melt flows polyetherimide siloxanes composition, manufacture method and product prepared therefrom | 沙特基础工业全球技术有限公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-106283265-A | A kind of preparation method of the microcosmic finely dispersed zirconium phosphate fire-retardant spandex of synergistic | 浙江华峰氨纶股份有限公司 | 2017-01-04 | — | — | CN | disclosed |
| CN-106211777-A | The seven phosphorus derivative compounds as fire retardant | 巴斯夫欧洲公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-104744587-A | SINGLE CHAIN FC POLYPEPTIDES | UCB PHARMA SA | 2015-07-01 | — | — | CN | disclosed |
| CN-1333828-B | Compositions and methods for increasing bone mineralization | UCB PHARMA SA | 2015-05-13 | — | — | CN | disclosed |
| CN-101495510-B | Single chain FC polypeptides | UCB PHARMA SA | 2015-02-25 | — | — | CN | disclosed |
| CN-102228241-A | Health-care food capable of tonifying brain, enhancing intelligence and enhancing memory and preparation method thereof | RUI ZHAO | 2011-11-02 | — | — | CN | disclosed |
| WO-2009051608-A2 | A NOVEL METHOD FOR POLYMER RDP-CLAY NANOCOMPOSITES AND MECHANISMS FOR POLYMER/POLYMER BLENDING | GLEN BURNIE TECHNOLOGIES (US) | 2009-04-23 | — | — | WO | disclosed |
| CN-101031577-A | Poly (arylene ether) composition | GEN ELECTRIC (US) | 2007-09-05 | — | — | CN | disclosed |