Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4078884 | 0.88 | ALDH1A1 (0.32) | MCL1L3MBTL1POLBKDM4ETP53 | |
| SCHEMBL11738399 | 0.84 | MAPK1 (0.33) | MCL1L3MBTL1TP53 | |
| SCHEMBL4804594 | 0.84 | ALDH1A1 (0.33) | MCL1ALDH1A1 | |
| SCHEMBL4077712 | 0.76 | SIRT1 (0.35) | MCL1L3MBTL1KDM4ESIRT1 | |
| SCHEMBL932332 | 0.74 | — | — | |
| SCHEMBL22468834 | 0.74 | — | — | |
| SCHEMBL9289233 | 0.72 | TSHR (0.35) | ALDH1A1SLC6A1SLC6A11TSHRLMNA | |
| SCHEMBL15659956 | 0.72 | MCL1 (0.65) | MCL1L3MBTL1POLBTP53GAA | |
| SCHEMBL3553694 | 0.72 | MCL1 (0.60) | MCL1L3MBTL1POLBKDM4E | |
| SCHEMBL28635174 | 0.72 | CA1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009049018-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2009049018-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-04-16 | — | — | WO | disclosed |
| WO-2007051255-A1 | PROCESS FOR THE PREPARATION OF COMPOUNDS CONTAINING AN AZACYCLIC RING SYSTEM | THE UNIVERSITY OF SYDNEY (AU) | 2007-05-10 | — | — | WO | disclosed |
| US-5407966-A | Recyclable thermoplastic foam with a high glass transition temperature II | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-18 | — | — | US | disclosed |
| US-3976677-A | Process for carboxylating organic substrates with carbon dioxide in hydrocarbon solvents | MONTEDISON S.P.A. (IT) | 1976-08-24 | — | — | US | disclosed |