SCHEMBL3975255

SCHEMBL3975255

CCO[Si](CCN1C(=O)CCC1=O)(OCC)OCC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.37
MGLL Q99685 1/20 0.37
HTT P42858 2/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MEN1 O00255 4/20 0.34
KMT2A Q03164 4/20 0.34
POLB P06746 2/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 2/20 0.31
BRD4 O60885 1/20 0.30
BRD2 P25440 1/20 0.30
GAA P10253 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA9 Q16790 1/20 0.30
CYP1A2 P05177 1/20 0.30
HTR1A P08908 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12979623 0.89 FAAH (0.41) FAAHMGLLHTTHPGDSMN1; SMN2
SCHEMBL3354841 0.77 FAAH (0.41) FAAHMGLLHTTHPGDSMN1; SMN2
SCHEMBL3979499 0.75 KMT2A (0.45) SMN1; SMN2MEN1KMT2AALDH1A1BRD4
SCHEMBL9893563 0.74 CYP1A2 (0.30) ALDH1A1CYP1A2
SCHEMBL27028181 0.73
SCHEMBL3978780 0.72 CYP1A2 (0.47) HPGDSMN1; SMN2CYP1A2CYP2C19
SCHEMBL1825898 0.69 FAAH (0.50) FAAHMGLLHTTHPGDSMN1; SMN2
SCHEMBL13322218 0.69 MEN1 (0.45) FAAHMGLLHTTHPGDSMN1; SMN2
SCHEMBL2800309 0.69 SMN1; SMN2 (0.46) HTTSMN1; SMN2MEN1KMT2AALDH1A1
SCHEMBL7259486 0.69 SMN1; SMN2 (0.44) FAAHMGLLHTTHPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6020449-A Alkoxy-crosslinking RTV1 silicone rubber mixtures WACKER-CHEMIE GMBH (DE) 2000-02-01 US claimed
CN-101506458-A Adhesive body sealed by means of silicone SIKA TECHNOLOGY AG (CH) 2009-08-12 CN disclosed
US-20090191375-A1 ADHESIVE JOINT SEALED WITH SILICONE SIKA TECHNOLOGY AG (CH) 2009-07-30 US disclosed
EP-2057341-A1 ADHESIVE JOINT SEALED WITH SILICONE Sika Technology AG (CH) 2009-05-13 EP disclosed
WO-2008000833-A1 ADHESIVE JOINT SEALED WITH SILICONE SIKA TECHNOLOGY AG (CH) 2008-01-03 WO disclosed
EP-1873344-A1 Silicone sealed bonding Sika Technology AG (CH) 2008-01-02 EP disclosed
US-6018011-A OBTAINED BY REACTING A POLYORGANOSILOXANE, WITH A REACTION PRODUCT OF AN ORGANOSILANE OF GIVEN FORMULA AND N-1-((METHYLDIETHOXYSILOXY)DIETHOXYSILYL)ETHYL-2-PYRROLIDONE; USE IN ALKOXY-CROSSLINKING RTV SILICONE RUBBER MIXTURES HUELS SILICONE GMBH (DE) 2000-01-25 US disclosed
US-6001948-A BASED ON HYDROXY-TERMINATED POLYDIORGANOSILOXANES CONTAINING A TRIALKOXYSILANE WITH A SUBSTITUTED AMIDOALKYL RADICAL, WHICH CAN BE PREPARED USING CONVENTIONAL MIXING TECHNOLOGIES. WACKER-CHEMIE GMBH (DE) 1999-12-14 US disclosed
EP-0885931-A2 One-component alkoxy group containing RTV-systems Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) 1998-12-23 EP disclosed