Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849142 | 0.87 | SLC6A4 (0.55) | SLC6A4GSRSLC6A2SLC6A3HRH3 | |
| SCHEMBL10021745 | 0.84 | IGLV6-57 (0.51) | SLC6A9SLC6A4HTR1ASLC6A2SLC6A3 | |
| SCHEMBL11748001 | 0.84 | SLC6A9 (0.50) | SLC6A9SLC6A4GSRPPARGPPARA | |
| SCHEMBL2232687 | 0.83 | FFAR1 (0.41) | SLC6A9SLC6A4PPARGPPARASLC6A2 | |
| SCHEMBL2773472 | 0.82 | SLC6A9 (0.52) | SLC6A9SLC6A4HTR1APPARGPPARA | |
| SCHEMBL11750911 | 0.82 | SLC6A4 (0.60) | SLC6A4GSRSLC6A2SLC6A3HRH3 | |
| SCHEMBL11754821 | 0.82 | SLC6A4 (0.60) | SLC6A9SLC6A4HTR1AGSRPPARG | |
| SCHEMBL11750036 | 0.82 | SLC6A4 (0.60) | SLC6A9SLC6A4HTR1AGSRPPARG | |
| SCHEMBL1582685 | 0.81 | SLC6A9 (0.56) | SLC6A9SLC6A4HTR1APPARGPPARA | |
| SCHEMBL13042191 | 0.81 | SLC6A9 (0.54) | SLC6A9SLC6A4HTR1ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103333058-B | The synthetic method of β-alkoxyl alcohol compounds | JIANGSU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2015-09-23 | — | — | CN | disclosed |
| CN-103333058-A | Beta-alkoxy alcohol compound synthesis method | UNIV JIANGSU SCIENCE & TECH | 2013-10-02 | — | — | CN | disclosed |
| US-7473705-B2 | Hexafluoroisopropanol substituted ether derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-01-06 | — | — | US | disclosed |
| EP-1802566-B1 | HEXAFLUOROISOPROPANOL SUBSTITUTED ETHER DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2008-11-26 | — | — | EP | disclosed |
| EP-1802566-A1 | HEXAFLUOROISOPROPANOL SUBSTITUTED ETHER DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006037480-A1 | HEXAFLUOROISOPROPANOL SUBSTITUTED ETHER DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2006-04-13 | — | — | WO | disclosed |
| US-20060074115-A1 | Novel hexafluoroisopropanol substituted ether derivatives | HOFFMANN-LA ROCHE INC. | 2006-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074115-A1 | Novel hexafluoroisopropanol substituted ether derivatives | NR1H3, NR1H2, NR1I2 | SLC6A9 2716/4885SLC6A4 2913/4885HTR1A 1893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.