SCHEMBL2849142

SCHEMBL2849142

OCC(Oc1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 8/20 0.55
GSR P00390 1/20 0.52
SLC6A2 P23975 2/20 0.44
SLC6A3 Q01959 2/20 0.44
KCNK2 O95069 1/20 0.44
KCNH2 Q12809 1/20 0.44
CACNA1C Q13936 1/20 0.44
F9 P00740 1/20 0.42
F10 P00742 1/20 0.42
PLAU P00749 1/20 0.42
SLC7A5 Q01650 5/20 0.41
HRH3 Q9Y5N1 1/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11748001 0.88 SLC6A9 (0.50) SLC6A4GSRSLC6A2SLC6A3CYP1A2
SCHEMBL14967332 0.87 SLC6A4 (0.53) SLC6A4GSRSLC6A2SLC6A3KCNK2
SCHEMBL11750036 0.87 SLC6A4 (0.60) SLC6A4GSR
SCHEMBL11754821 0.87 SLC6A4 (0.60) SLC6A4GSRSLC6A2SLC6A3KCNK2
SCHEMBL11750911 0.87 SLC6A4 (0.60) SLC6A4GSRSLC6A2SLC6A3KCNK2
SCHEMBL3976067 0.87 SLC6A9 (0.52) SLC6A4GSRSLC6A2SLC6A3KCNK2
Acrylic Acid SCHEMBL27803176 0.86 GSR (0.45) SLC6A4GSRKDM4EMEN1ALOX15
SCHEMBL14967119 0.84 SRD5A2 (0.53) SLC6A4GSRHRH3TSHRKMT2A
SCHEMBL28137895 0.83 SLC6A4 (0.61) SLC6A4SLC6A2SLC6A3KCNK2KCNH2
SCHEMBL11755613 0.82 SLC6A4 (0.56) SLC6A4GSRSLC6A2SLC6A3KCNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109880062-A A kind of cross-linkable solidifying material and its continuous production method 广东博兴新材料科技有限公司 2019-06-14 CN claimed
CN-109876858-A One kind preparation method of (methyl) acrylate substance and the application of 2- acrylamide-2-methyl propane sulfonic 广东博兴新材料科技有限公司 2019-06-14 CN claimed
CN-109776312-A A kind of preparation method of acryloxy propionic ester type compound 衡阳师范学院 2019-05-21 CN claimed
CN-109734586-A Treatment method for recycling (methyl) acrylic acid in esterification reaction system 广东博兴新材料科技有限公司 2019-05-10 CN claimed
CN-106699523-A Synthetic method of o-phenyl phenoxyethanol 上海飞凯光电材料股份有限公司 2017-05-24 CN claimed
CN-102070415-B Method for preparing o-phenylphenoxyethanol SHANGHAI JINSHAN CHEMICAL CO LTD 2013-07-10 CN claimed
CN-102070415-A Method for preparing o-phenylphenoxyethanol SHANGHAI JINSHAN CHEMICAL CO LTD 2011-05-25 CN claimed
CN-117362162-A Preparation method of carbonyl compound 中国科学院大连化学物理研究所 2024-01-09 CN disclosed
CN-117004958-A Fine-washing phosphorus-free degreasing powder for aluminum-iron-zinc co-tank, and preparation method and application thereof 湖南金裕环保科技有限公司 2023-11-07 CN disclosed
US-20200102323-A1 ACC INHIBITORS AND USES THEREOF SCHRÖDINGER, INC. 2020-04-02 US disclosed
US-10472374-B2 ACC inhibitors and uses thereof GILEAD APOLLO, LLC (US) 2019-11-12 US disclosed
EP-3329919-B1 ACC INHIBITORS AND USES THEREOF GILEAD APOLLO LLC (US) 2019-11-06 EP disclosed
CN-109880062-A A kind of cross-linkable solidifying material and its continuous production method 广东博兴新材料科技有限公司 2019-06-14 CN disclosed
US-20090138208-A1 IMMUNOGLOBULIN G BINDING POCKET GE HEALTHCARE BIO-SCIENCES AB (SE) 2009-05-28 US disclosed
US-20060014735-A1 Use of urea variants as affinity ligands CYTIVA BIOPROCESS R&D AB (SE) 2006-01-19 US disclosed
US-6743820-B2 ADMINISTERING TO THE EPITHELIUM AN EFFECTIVE AMOUNT OF AN AGENT COMPRISING: A) AT LEAST ONE AROMATIC GROUP; B) AT LEAST ONE SULFATE OR METALSULFATE GROUP AND C) A SUBSTITUENT GROUPS ON THE RING UNIVERSITY OF TOLEDO 2004-06-01 US disclosed
WO-2004039843-A1 IMMUNOGLOBULIN G BINDING POCKET AMERSHAM BIOSCIENCES AB (SE) 2004-05-13 WO disclosed
US-20020052408-A1 Methods for protection of stratified squamous epithelium against injury by noxious substances and novel agents for use therefor NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-05-02 US disclosed
WO-2002004411-A1 METHODS FOR PROTECTION OF STRATIFIED SQUAMOUS EPITHELIUM AGAINST INJURY BY NOXIOUS SUBSTANCES AND NOVEL AGENTS FOR USE THEREFOR THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2002-01-17 WO disclosed
US-4255152-A USING A DISPERSE DYE, WATER, AND AN ADDUCT OF ETHYLENE, PROPYLENE, OR STYRENE OXIDE AND A CYCLIC-SUBSTITUTED PHENOL; LEVELLING CIBA-GEIGY CORPORATION (US) 1981-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200102323-A1 ACC INHIBITORS AND USES THEREOF ACACA, ACACB, ACAT2 SLC6A4 4169/4885GSR 1846/4885SLC6A2 3767/4885
US-20060014735-A1 Use of urea variants as affinity ligands IGLV6-57, FCGR2A, FCGR3B SLC6A4 3931/4885GSR 4317/4885SLC6A2 3363/4885
US-10472374-B2 ACC inhibitors and uses thereof ACACA, ACACB, ACAT2 SLC6A4 4169/4885GSR 1846/4885SLC6A2 3767/4885
US-20020052408-A1 Methods for protection of stratified squamous epithelium against injury by noxious substances and novel agents for use therefor HRH2, NR1H4, NCEH1 SLC6A4 2074/4885GSR 637/4885SLC6A2 2815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.