⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451573 | 0.84 | — | — | |
| SCHEMBL542409 | 0.84 | — | — | |
| SCHEMBL9411280 | 0.81 | — | — | |
| SCHEMBL42835 | 0.81 | — | — | |
| SCHEMBL3233256 | 0.65 | — | — | |
| SCHEMBL402036 | 0.58 | — | — | |
| SCHEMBL1343696 | 0.55 | KDM4E (0.34) | — | |
| SCHEMBL6618 | 0.55 | — | — | |
| SCHEMBL5360866 | 0.55 | — | — | |
| SCHEMBL45941 | 0.55 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240308992-A1 | DRAK2 INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Biopolar Youtang(Guangdong) Pharmaceutical Co., Ltd. (CN) | 2024-09-19 | — | — | US | claimed |
| WO-2024097746-A1 | ALKENE CYCLOPROPANATION WITH NICKEL CATALYST ENHANCER AND IMPROVED REARRANGEMENT REACTION | CONAGEN INC. (US) | 2024-05-10 | — | — | WO | claimed |
| CN-117430622-A | Derivatives of heterocyclic compounds as pest control agents | 拜耳公司 | 2024-01-23 | — | — | CN | claimed |
| EP-3864015-B1 | PROCESS FOR THE PREPARATION OF IMIDAZOLE DERIVATEIVES | BAYER AG (DE) | 2023-05-10 | — | — | EP | claimed |
| CN-110312718-B | Heterocyclene derivatives as pest control agents | 拜耳公司 | 2023-02-28 | — | — | CN | claimed |
| EP-3864016-B1 | PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLE DERIVATIVES | BAYER AG (DE) | 2022-09-14 | — | — | EP | claimed |
| US-20220009930-A1 | PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2022-01-13 | — | — | US | claimed |
| US-20210380611-A1 | PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-12-09 | — | — | US | claimed |
| EP-3864016-A1 | PROCESS FOR PREPARING SUBSTITUTED IMIDAZOLE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2021-08-18 | — | — | EP | claimed |
| EP-3864015-A1 | PROCESS FOR PREPARING IMIDAZOLE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2021-08-18 | — | — | EP | claimed |
| WO-2009017719-A2 | MODULATORS OF CCR9 RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2009-02-05 | — | — | WO | claimed |
| WO-2008116339-A2 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-10-02 | — | — | WO | claimed |
| CN-101048388-A | Quinazolinone derivatives and their use as B-Raf inhibitors | ASTRAZENECA AB (SE) | 2007-10-03 | — | — | CN | claimed |
| EP-1789399-A1 | QUINAZOLINONE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS | AstraZeneca AB (SE) | 2007-05-30 | — | — | EP | claimed |
| WO-2007001406-A2 | ARYL-CONTAINING MACROCYCLIC COMPOUNDS | CHIRON CORPORATION (US) | 2007-01-04 | — | — | WO | claimed |
| WO-2006024834-A1 | QUINAZOLINONE DERIVATIVES AND THEIR USE AS B-RAF INHIBITORS | ASTRAZENECA AB (SE) | 2006-03-09 | — | — | WO | claimed |
| EP-0847974-B1 | Process for the preparation of cyclopropylacetylene and its derivatives | KURARAY CO (JP) | 2002-06-05 | — | — | EP | claimed |
| US-5955627-A | Process for the preparation of cyclopropylacetylene derivatives | KURARAY CO., LTD. (JP) | 1999-09-21 | — | — | US | claimed |
| EP-0847974-A1 | Process for the preparation of cyclopropylacetylene and its derivatives | KURARAY CO., LTD. (JP) | 1998-06-17 | — | — | EP | claimed |
| EP-0569760-B1 | Process for the preparation of 1-cyclopropylbutan-1,3-dione | BASF AG (DE) | 1996-10-30 | — | — | EP | claimed |