SCHEMBL3976170

SCHEMBL3976170

Oc1cccc(C2(c3cccc(O)c3)C3CC4CC(C3)CC2C4)c1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.41
OPRD1 P41143 4/20 0.40
OPRK1 P41145 4/20 0.40
OPRM1 P35372 4/20 0.40
HSD11B1 P28845 4/20 0.40
FAAH O00519 1/20 0.40
CA12 O43570 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CA2 P00918 1/20 0.39
LMNA P02545 1/20 0.39
CYP3A4 P08684 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA14 Q9ULX7 1/20 0.39
CA5B Q9Y2D0 1/20 0.39
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23198930 0.78 CYP3A4 (0.39) OPRK1OPRM1HSD11B1CA12ALDH1A1
SCHEMBL24173748 0.78 CYP3A4 (0.39) OPRK1OPRM1HSD11B1CA12ALDH1A1
SCHEMBL23620590 0.78 HSD11B1 (0.57) HSD11B1
SCHEMBL175542 0.76 HSD11B1 (0.41) ALOX5APHSD11B1CA12ALDH1A1CA2
SCHEMBL1353430 0.76 HSD11B1 (0.52) ALOX5APHSD11B1
SCHEMBL3754199 0.76 MEN1 (0.59) ALOX5APHSD11B1
SCHEMBL419753 0.76 MEN1 (0.59) OPRD1OPRK1OPRM1FAAHALDH1A1
SCHEMBL2710599 0.75 GAA (0.42) ALOX5APHSD11B1CA12ALDH1A1CA2
SCHEMBL3025215 0.75 HSD11B1 (0.73) HSD11B1
SCHEMBL17149169 0.75 OPRD1 (0.42) ALOX5APOPRD1OPRK1OPRM1HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed