SCHEMBL3976477

SCHEMBL3976477

Cc1nc(-c2ccc(O)cc2)c(C)nc1-c1ccc(O)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.48
MEN1 O00255 4/20 0.48
ESR1 P03372 2/20 0.48
ESR2 Q92731 1/20 0.48
MAPT P10636 5/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
SENP1 Q9P0U3 1/20 0.44
POLB P06746 1/20 0.44
USP2 O75604 2/20 0.44
NPC1 O15118 2/20 0.44
NFKB1 P19838 2/20 0.44
RAB9A P51151 2/20 0.44
TP53 P04637 1/20 0.44
PKM P14618 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ACHE P22303 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11421241 0.83 MEN1 (0.69) KMT2AMEN1MAPTALDH1A1HPGD
SCHEMBL7120242 0.79 JAK3 (0.49) KMT2AMEN1ESR1ESR2MAPT
SCHEMBL9159542 0.78 MEN1 (0.62) KMT2AMEN1ESR1ESR2MAPT
SCHEMBL2126247 0.78 DGAT1 (0.65)
SCHEMBL10945797 0.74 KDM4E (0.54) KMT2AMEN1MAPTALDH1A1HPGD
SCHEMBL15676723 0.72 KDM4E (0.44) KMT2AMEN1ESR1ESR2MAPT
SCHEMBL19390516 0.71 SENP1 (0.52) KMT2AMEN1ESR1ESR2MAPT
SCHEMBL21389064 0.71 ESR1 (0.48) KMT2AMEN1ESR1ESR2SENP1
SCHEMBL13515891 0.70 KDM4E (0.50) KMT2AMEN1MAPTALDH1A1HPGD
SCHEMBL10205869 0.70 TDP1 (0.54) KMT2AMEN1MAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6065212-A None JP disclosed
CN-101062975-B Aromatic polycarbonate resin, process for producing the same, molding material for optical parts, and optical parts IDEMITSU KOSAN CO 2012-05-30 CN disclosed
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
EP-1361241-B1 Process for producing raw polycarbonate resin material and producing polycarbonate resin IDEMITSU KOSAN CO (JP) 2005-08-24 EP disclosed
US-20050143553-A1 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD (JP) 2005-06-30 US disclosed
EP-1178068-B1 PROCESSES FOR PRODUCING RAW POLYCARBONATE RESIN MATERIAL AND PRODUCING POLYCARBONATE RESIN IDEMITSU KOSAN CO (JP) 2005-05-18 EP disclosed
EP-1469026-A1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDINGMATERIAL AND OPTICAL PART IDEMITSU KOSAN CO., LTD. (JP) 2004-10-20 EP disclosed
EP-0896975-B1 POLYCARBONATE, AND MOLDING AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN CO (JP) 2003-06-04 EP disclosed
EP-1288242-A2 Polycarbonate, and molding and electrophotograpic photoreceptor prepared therefrom Idemitsu Kosan Co., Ltd. (JP) 2003-03-05 EP disclosed
EP-1178068-A1 PROCESSES FOR PRODUCING RAW POLYCARBONATE RESIN MATERIAL AND PRODUCING POLYCARBONATE RESIN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-02-06 EP disclosed
US-6136521-A POLYORGANOSILOXANE-CONTAINING POLYCARBONATE IDEMITSU KOSAN CO., LTD. (JP) 2000-10-24 US disclosed
EP-0896975-A1 POLYCARBONATE, AND MOLDING AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1999-02-17 EP disclosed
EP-0837085-A1 POLYCARBONATE-BASE POLYMER, PRODUCTION PROCESS, RESIN COATING FLUID PREPARED THEREFROM, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR PREPARED THEREFROM IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-04-22 EP disclosed
JP-H0665212-A PYRAZINE DERIVATIVE AND ITS PRODUCTION IDEMITSU KOSAN CO LTD 1994-03-08 JP disclosed