Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255931 | 0.89 | TRPV1 (0.69) | TRPV1 | |
| Amg-517 SCHEMBL3976558 | 0.87 | TRPV1 (0.84) | TRPV1 | |
| Amg-517 SCHEMBL3976572 | 0.87 | TRPV1 (0.84) | TRPV1 | |
| SCHEMBL1040404 | 0.87 | TRPV1 (0.80) | TRPV1 | |
| SCHEMBL1041235 | 0.84 | TRPV1 (0.76) | TRPV1 | |
| SCHEMBL1039230 | 0.84 | TRPV1 (0.81) | TRPV1 | |
| SCHEMBL1040601 | 0.83 | TRPV1 (0.80) | TRPV1 | |
| SCHEMBL1042350 | 0.83 | TRPV1 (0.82) | TRPV1 | |
| SCHEMBL5968285 | 0.81 | TRPV1 (0.79) | TRPV1 | |
| Amg-517 SCHEMBL29389509 | 0.81 | TRPV1 (1.00) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2056798-A2 | SORBIC ACID ANALOG CO-CRYSTALS | Amgen, Inc (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008024437-A2 | SORBIC ACID ANALOG CO-CRYSTALS | AMGEN INC. (US) | 2008-02-28 | — | — | WO | disclosed |
| US-20080051453-A1 | Sorbic acid analog co-crystals | AMGEN INC. | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051453-A1 | Sorbic acid analog co-crystals | SORBS1, XDH, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | TRPV1 863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.