Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | TYMP | P19971 | 3/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511441 | 0.89 | MAPT (0.58) | MAPTPARP1ALDH1A1NOTUMPDE3B | |
| SCHEMBL692156 | 0.78 | MAPT (0.56) | MAPTPARP1ALDH1A1LMNAHTT | |
| SCHEMBL6535580 | 0.78 | MAPT (0.61) | MAPTPARP1ALDH1A1NOTUMPDE4A | |
| SCHEMBL21223184 | 0.78 | MAPT (0.61) | MAPTPARP1ALDH1A1NOTUMPDE4A | |
| SCHEMBL27739470 | 0.78 | MAPT (1.00) | MAPTPARP1ALDH1A1NOTUMPDE4A | |
| SCHEMBL8108278 | 0.77 | MAPT (0.47) | MAPTPARP1ALDH1A1LMNAHTT | |
| SCHEMBL6535945 | 0.77 | MAPT (0.56) | MAPTPARP1ALDH1A1NOTUMPDE4A | |
| SCHEMBL18628562 | 0.75 | MAPT (0.58) | MAPTPARP1ALDH1A1LMNAHTT | |
| SCHEMBL4428264 | 0.75 | MAPT (0.58) | MAPTPARP1ALDH1A1HTTNOTUM | |
| SCHEMBL149989 | 0.74 | MAPT (0.57) | MAPTPARP1ALDH1A1NOTUMHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114751912-B | Application of isopentenyl substituted bisphenylpyridone compound | 昆明医科大学 | 2023-03-07 | — | — | CN | claimed |
| CN-114751912-A | New application of isopentenyl substituted bisphenylpyridone compound | 昆明医科大学 | 2022-07-15 | — | — | CN | claimed |
| CN-117946308-A | Bridged pyridine amino hafnium catalyst, and preparation method and application thereof | 中国石油天然气股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-114751912-B | Application of isopentenyl substituted bisphenylpyridone compound | 昆明医科大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-114751912-B | Application of isopentenyl substituted bisphenylpyridone compound | 昆明医科大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-114751912-B | Application of isopentenyl substituted bisphenylpyridone compound | 昆明医科大学 | 2023-03-07 | — | — | CN | disclosed |
| CN-115645340-A | Preparation method of rhizoma anemarrhenae total ketone extract and application of rhizoma anemarrhenae total ketone extract in cosmetics | 爱生泽(上海)生物科技有限公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115429736-A | Preparation method of rhizoma anemarrhenae total saponin extract and application of rhizoma anemarrhenae total saponin extract in cosmetics | 爱生泽(上海)生物科技有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-114751912-A | New application of isopentenyl substituted bisphenylpyridone compound | 昆明医科大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-114751912-A | New application of isopentenyl substituted bisphenylpyridone compound | 昆明医科大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-114751912-A | New application of isopentenyl substituted bisphenylpyridone compound | 昆明医科大学 | 2022-07-15 | — | — | CN | disclosed |
| CN-106511728-B | Preparation method of gardenia golden flower dropping pills | 承德医学院 | 2021-09-17 | — | — | CN | disclosed |
| CN-113214233-A | Method for extracting and purifying mangiferin from mango seeds | 贺州学院 | 2021-08-06 | — | — | CN | disclosed |
| CN-113041272-A | Application of total flavone extract of abelmoschus manihot | 河北工程大学 | 2021-06-29 | — | — | CN | disclosed |
| CN-111617212-A | A Chinese medicinal composition for treating dermatoses | 颐康医药科技(天津)有限公司 | 2020-09-04 | — | — | CN | disclosed |
| CN-111505185-A | Method for enriching and purifying mangiferin from gentiana carthami and detection method thereof | 贵州中医药大学 | 2020-08-07 | — | — | CN | disclosed |
| CN-108478500-B | Composition for oral cavity and application thereof | 弘美制药（中国）有限公司 | 2020-07-10 | — | — | CN | disclosed |
| CN-107050410-B | Traditional Chinese medicine composition and preparation method and application thereof | 首都医科大学附属北京中医医院 | 2020-07-03 | — | — | CN | disclosed |
| WO-2009054544-A1 | AMPA RECEPTOR ANTAGONISTS FOR PARKINSON'S DISEASE AND MOVEMENT DISORDERS | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-04-30 | — | — | WO | disclosed |
| US-6071913-A | 2-(1H-TETRAZOL-5-YL)-4'-(AS-TRIAZIN-YLMETHYL)BIPHENYLS; CARDIOVASCULAR DISEASES, ESPECIALLY HYPERTENSION AND CONGESTIVE HEART FAILURE | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2000-06-06 | — | — | US | disclosed |