Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640560 | 0.95 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL2229452 | 0.95 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL6050828 | 0.95 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL4712511 | 0.95 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL8640554 | 0.95 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL286072 | 0.95 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL2569149 | 0.95 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL10891279 | 0.95 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL3658217 | 0.95 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 | |
| SCHEMBL3558101 | 0.95 | CYP2D6 (0.32) | CYP2D6MEN1KMT2ALMNAHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8252784-B2 | Photoactivable nitrogen bases | BASF SE (DE) | 2012-08-28 | — | — | US | disclosed |
| US-7538104-B2 | Photoactivable nitrogen bases | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-05-26 | — | — | US | disclosed |
| US-20090076200-A1 | Letter with continuation application | BAUDIN GISELE | 2009-03-19 | — | — | US | disclosed |
| EP-1436297-B1 | PHOTOACTIVABLE NITROGEN BASES | CIBA SC HOLDING AG (CH) | 2007-04-25 | — | — | EP | disclosed |
| US-20040242867-A1 | Photoactivable nitrogen bases | CIBA CORPORATION | 2004-12-02 | — | — | US | disclosed |
| EP-1436297-A1 | PHOTOACTIVABLE NITROGEN BASES | Ciba Specialty Chemicals Holding Inc. (CH) | 2004-07-14 | — | — | EP | disclosed |
| US-6583133-B1 | Especially against Gram-positive organisms, e.g. methicillin-sensitive (MSSA) and methicillin- resistant (MRSA) staphylococci, enterococci and pneumococci | BASILEA PHARMACEUTICA AG (CH) | 2003-06-24 | — | — | US | disclosed |
| WO-2003033500-A1 | PHOTOACTIVABLE NITROGEN BASES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242867-A1 | Photoactivable nitrogen bases | CBR3, NR2E3, RCOR3 | CYP2D6 665/4885MEN1 4688/4885KMT2A 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.