SCHEMBL3976943

SCHEMBL3976943

ClC(c1ccccc1Br)(c1c(Br)c(Br)c(Br)c(Br)c1Br)C(Br)(Br)Br

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA5A P35218 1/20 0.36
CA9 Q16790 1/20 0.36
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3977115 0.77 TSHR (0.42) ALDH1A1
SCHEMBL94425 0.74 CA1 (0.38) CA1CA2CA5ACA9ALDH1A1
SCHEMBL4948729 0.74 CA1 (0.38) CA1CA2CA5ACA9ALDH1A1
SCHEMBL6683583 0.73 CA2 (0.41) CA1CA2CA5ACA9CA4
SCHEMBL30343002 0.73 CA2 (0.41) CA1CA2CA5ACA9CA4
SCHEMBL4810533 0.73 CA1 (0.41) CA1CA2CA5ACA9CA4
SCHEMBL10656679 0.72 CA1 (0.43) CA1CA2CA5ACA9CA4
SCHEMBL4949691 0.71 CA1 (0.39) CA1CA2CA5ACA9ALDH1A1
Ethane SCHEMBL9862554 0.71 CA1 (0.36) CA1CA2CA5ACA9ALDH1A1
SCHEMBL4944376 0.71 CA1 (0.36) CA1CA2CA5ACA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2057110-A1 PREPARATION OF DECAHALODIPHENYL ETHANE Albermarle Corporation (US) 2009-05-13 EP claimed
WO-2008027737-A1 PREPARATION OF DECAHALODIPHENYL ETHANE ALBEMARLE CORPORATION (US) 2008-03-06 WO claimed
US-20080058458-A1 PREPARATION OF DECAHALODIPHENYL ETHANE ALBEMARLE CORPORATION (US) 2008-03-06 US claimed
EP-2057110-A1 PREPARATION OF DECAHALODIPHENYL ETHANE Albermarle Corporation (US) 2009-05-13 EP disclosed
WO-2008027737-A1 PREPARATION OF DECAHALODIPHENYL ETHANE ALBEMARLE CORPORATION (US) 2008-03-06 WO disclosed
US-20080058458-A1 PREPARATION OF DECAHALODIPHENYL ETHANE ALBEMARLE CORPORATION (US) 2008-03-06 US disclosed