SCHEMBL3977115

SCHEMBL3977115

ClC(c1ccccc1)(c1c(Br)c(Br)c(Br)c(Br)c1Br)C(Br)(Br)Br

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
CYP1A2 P05177 1/20 0.35
KCNN4 O15554 2/20 0.32
ALDH1A1 P00352 2/20 0.32
TDP1 Q9NUW8 1/20 0.31
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3976943 0.77 CA1 (0.36) ALDH1A1
SCHEMBL4949944 0.73 KCNN4 (0.35) TSHRKCNN4ALDH1A1TDP1
SCHEMBL652269 0.73 KCNN4 (0.35) TSHRKCNN4ALDH1A1TDP1
SCHEMBL10940043 0.72 TSHR (0.65) TSHRCYP1A2KCNN4ALDH1A1PTPN1
SCHEMBL15064283 0.72 ALDH1A1 (0.38) TSHRCYP1A2KCNN4ALDH1A1TDP1
SCHEMBL4813303 0.72 KCNN4 (0.38) TSHRCYP1A2KCNN4ALDH1A1TDP1
SCHEMBL4952285 0.70 KCNN4 (0.33) TSHRKCNN4ALDH1A1TDP1
SCHEMBL819165 0.68 TSHR (0.58) TSHRCYP1A2KCNN4ALDH1A1PTPN1
SCHEMBL4952329 0.67 KCNN4 (0.34) TSHRKCNN4ALDH1A1TDP1
SCHEMBL4947666 0.67 KCNN4 (0.34) TSHRKCNN4ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2057110-A1 PREPARATION OF DECAHALODIPHENYL ETHANE Albermarle Corporation (US) 2009-05-13 EP disclosed
WO-2008027737-A1 PREPARATION OF DECAHALODIPHENYL ETHANE ALBEMARLE CORPORATION (US) 2008-03-06 WO disclosed
US-20080058458-A1 PREPARATION OF DECAHALODIPHENYL ETHANE ALBEMARLE CORPORATION (US) 2008-03-06 US disclosed