SCHEMBL3977182

SCHEMBL3977182

N#Cc1cc(C(=O)O)ns1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.35
ALOX15 P16050 2/20 0.34
TSHR P16473 2/20 0.34
HIF1A Q16665 1/20 0.34
ALDH1A1 P00352 3/20 0.32
ACMSD Q8TDX5 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MAPT P10636 2/20 0.31
DAO P14920 2/20 0.31
KDM6B O15054 1/20 0.31
TET3 O43151 1/20 0.31
KDM4A O75164 1/20 0.31
BBOX1 O75936 1/20 0.31
KDM5A P29375 1/20 0.31
KDM5C P41229 1/20 0.31
ASPH Q12797 1/20 0.31
KDM4D Q6B0I6 1/20 0.31
TET2 Q6N021 1/20 0.31
ALKBH5 Q6P6C2 1/20 0.31
KDM7A Q6ZMT4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL162060 0.70
SCHEMBL162059 0.70
SCHEMBL11322083 0.70 KDM4E (0.40) KDM4EALOX15TSHRHIF1AALDH1A1
SCHEMBL26103133 0.68
SCHEMBL13954549 0.68
SCHEMBL20928813 0.68
SCHEMBL17591776 0.64 SMYD3 (0.50) KDM4EALOX15TSHRHIF1AALDH1A1
SCHEMBL25468304 0.63 DAO (0.57) KDM4ETSHRALDH1A1MAPTDAO
SCHEMBL2116770 0.63 ALDH1A1 (0.50) KDM4EALOX15TSHRALDH1A1ACMSD
SCHEMBL3561099 0.63 CASP6 (0.35) KDM4EALOX15TSHRHIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109925545-B Injection device for autologous blood purification injection and preparation method thereof 北京华悦恒生健康管理有限公司 2022-03-01 CN claimed
CN-108951354-B Novel road shoulder building device for highway engineering and preparation method thereof 谢丽荟 2021-05-18 CN claimed
CN-109925545-B Injection device for autologous blood purification injection and preparation method thereof 北京华悦恒生健康管理有限公司 2022-03-01 CN disclosed
CN-108951354-B Novel road shoulder building device for highway engineering and preparation method thereof 谢丽荟 2021-05-18 CN disclosed
CN-108951354-A A kind of novel road engineering road shoulder builds device and preparation method thereof 谢丽荟 2018-12-07 CN disclosed
WO-2009060030-A1 HETEROARYL-SUBSTITUTED 2-PYRIDINYLMETHYLAMINE DERIVATIVES Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) 2009-05-14 WO disclosed
EP-2058306-A1 Heteroaryl-substituted 2-pyridinyl-methylamine derivatives SCHWARZ PHARMA AG (DE) 2009-05-13 EP disclosed