Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22405016 | 0.82 | RAB9A (0.51) | ALDH1A1MEN1KMT2ARAB9ACLK4 | |
| SCHEMBL3979224 | 0.80 | APP (0.43) | ALDH1A1MEN1KMT2AFFAR1RAB9A | |
| SCHEMBL22404982 | 0.80 | NPSR1 (0.57) | MEN1KMT2AFFAR1L3MBTL1RAB9A | |
| SCHEMBL11080118 | 0.80 | MEN1 (0.50) | MEN1KMT2AFFAR1RAB9ALTA4H | |
| SCHEMBL11153430 | 0.80 | MEN1 (0.62) | ALDH1A1MEN1KMT2AFFAR1RAB9A | |
| SCHEMBL24156362 | 0.80 | MEN1 (0.44) | ALDH1A1MEN1KMT2AFFAR1L3MBTL1 | |
| SCHEMBL18921120 | 0.79 | TUBB4A (0.46) | ALDH1A1MEN1KMT2AFFAR1RAB9A | |
| SCHEMBL3978242 | 0.79 | SLC6A4 (0.43) | ALDH1A1MEN1KMT2AFFAR1RAB9A | |
| SCHEMBL2313930 | 0.79 | MEN1 (0.55) | ALDH1A1MEN1KMT2AFFAR1RAB9A | |
| SCHEMBL20657592 | 0.78 | APP (0.50) | FFAR1RAB9ASMN1; SMN2NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291971-A1 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | WYETH (US) | 2009-11-26 | — | — | US | disclosed |
| US-20090291971-A1 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | WYETH (US) | 2009-11-26 | — | — | US | disclosed |
| US-20090291971-A1 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | WYETH (US) | 2009-11-26 | — | — | US | disclosed |
| WO-2009058937-A2 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | WYETH (US) | 2009-05-07 | — | — | WO | disclosed |
| WO-2009058937-A2 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | WYETH (US) | 2009-05-07 | — | — | WO | disclosed |
| US-4427437-A | PLANT GROWTH REGULATORS | ICI AUSTRALIA LIMITED (AU) | 1984-01-24 | — | — | US | disclosed |
| EP-0001187-B1 | 2-PHENOXY-PYRIMIDINES AND THEIR USE AS PESTICIDES | ICI AUSTRALIA LIMITED (AU) | 1983-12-07 | — | — | EP | disclosed |
| US-4248618-A | Derivatives of (pyrimidyloxy)phenoxy-alkanecarboxylic acid and herbicidal compositions thereof | ICI AUSTRALIA LIMITED (AU) | 1981-02-03 | — | — | US | disclosed |
| EP-0001187-A1 | 2-phenoxy-pyrimidines and their use as pesticides | ICI AUSTRALIA LIMITED (AU) | 1979-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291971-A1 | HETEROARYL ETHERS AND PROCESSES FOR THEIR PREPARATION | AHR, MALT1, ABL1 | ALDH1A1 1591/4885MEN1 1922/4885KMT2A 620/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.