Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.63 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.58 |
| ▸ | RXRA | P19793 | 1/20 | 0.58 |
| ▸ | RXRB | P28702 | 1/20 | 0.58 |
| ▸ | RXRG | P48443 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | THRA | P10827 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986580 | 1.00 | RARB (0.63) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL10871804 | 1.00 | RARB (0.63) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL9723851 | 1.00 | RARB (0.63) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL8769909 | 1.00 | RARB (0.63) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL9799861 | 1.00 | RARB (0.63) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL6266863 | 1.00 | RARB (0.63) | RARBPTPN11TP53TSHRPLA2G4B | |
| Hydrochloric Acid SCHEMBL8419152 | 0.99 | RARB (0.62) | RARBPTPN11TP53TSHRPLA2G4B | |
| Terephthalic Acid SCHEMBL10581511 | 0.97 | RXRA (0.62) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL7331535 | 0.97 | RARB (0.63) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL9647287 | 0.93 | RARB (0.59) | RARBPTPN11TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057173-A1 | AMIDES AS SPHINGOMYELINE INHIBITORS | Novartis AG (CH) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008022771-A1 | AMIDES AS SPHINGOMYELINE INHIBITORS | NOVARTIS AG (CH) | 2008-02-28 | — | — | WO | disclosed |
| US-6139946-A | Magnetic recording media incorporating a quaternary ammonium functional binder and magnetic pigment surface treated with compound having acidic and electron withdrawing functionalities | IMATION CORP. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0405974-B1 | Holographic operating optical apparatus | SEIKO INSTR INC (JP) | 1995-11-29 | — | — | EP | disclosed |
| EP-0518449-B1 | Optical interconnection apparatus | SEIKO INSTR INC (JP) | 1995-11-02 | — | — | EP | disclosed |
| EP-0371695-B1 | Liquid crystal device for providing a spatial light modulator for modulating a laser beam | SEIKO INSTR INC (JP) | 1995-02-01 | — | — | EP | disclosed |
| EP-0334340-B1 | Optically switching ferroelectric liquid crystal light valve | SEIKO INSTR INC (JP) | 1994-11-09 | — | — | EP | disclosed |
| US-5344586-A | Antiferroelectric liquid crystal compound and process for producing the same | SHOWA SHEEL SEKIYU KABUSHIKI KAISHA (JP) | 1994-09-06 | — | — | US | disclosed |
| US-5313321-A | Optically switching ferroelectric liquid crystal light valve having a pre-tilt angle of 60 to 80 degrees | SEIKO INSTRUMENTS INC. (JP) | 1994-05-17 | — | — | US | disclosed |
| EP-0518449-A1 | Optical interconnection apparatus | SEIKO INSTRUMENTS INC. (JP) | 1992-12-16 | — | — | EP | disclosed |
| US-5085498-A | OPTICALLY SWITCHING FERROELECTRIC LIQUID CRYSTAL LIGHT VALVE | SEIKO INSTRUMENTS INC. (JP) | 1992-02-04 | — | — | US | disclosed |
| EP-0302875-B1 | OPTICALLY ACTIVE NAPHTHALENE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN (GB) | 1991-02-27 | — | — | EP | disclosed |
| EP-0405974-A2 | Holographic operating optical apparatus | SEIKO INSTRUMENTS INC. (JP) | 1991-01-02 | — | — | EP | disclosed |
| EP-0402944-A2 | Light addressed liquid crystal light valve | SEIKO INSTRUMENTS INC. (JP) | 1990-12-19 | — | — | EP | disclosed |
| EP-0395113-A2 | Laser writing type liquid crystal light valve | SEIKO INSTRUMENTS INC. (JP) | 1990-10-31 | — | — | EP | disclosed |
| EP-0371695-A2 | Liquid crystal device for providing a spatial light modulator for modulating a laser beam | SEIKO INSTRUMENTS INC. (JP) | 1990-06-06 | — | — | EP | disclosed |
| EP-0341713-A2 | Optically active compounds, liquid crystal compositions comprising said compounds, and liquid crystal optical modulators using said compositions | HITACHI, LTD. (JP) | 1989-11-15 | — | — | EP | disclosed |
| EP-0334340-A2 | Optically switching ferroelectric liquid crystal light valve | SEIKO INSTRUMENTS INC. (JP) | 1989-09-27 | — | — | EP | disclosed |
| EP-0322862-A2 | Optically active compounds, their preparation and their use in liquid crystal compositions and liquid crystal optical modulators | HITACHI, LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0188222-A2 | Novel liquid cristalline compounds having substituents | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1986-07-23 | — | — | EP | disclosed |