Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.63 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.58 |
| ▸ | RXRA | P19793 | 1/20 | 0.58 |
| ▸ | RXRB | P28702 | 1/20 | 0.58 |
| ▸ | RXRG | P48443 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | THRA | P10827 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977527 | 1.00 | RARB (0.63) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL8986580 | 1.00 | RARB (0.63) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL10871804 | 1.00 | RARB (0.63) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL9723851 | 1.00 | RARB (0.63) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL8769909 | 1.00 | RARB (0.63) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL6266863 | 1.00 | RARB (0.63) | RARBPTPN11TP53TSHRPLA2G4B | |
| Hydrochloric Acid SCHEMBL8419152 | 0.99 | RARB (0.62) | RARBPTPN11TP53TSHRPLA2G4B | |
| Terephthalic Acid SCHEMBL10581511 | 0.97 | RXRA (0.62) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL7331535 | 0.97 | RARB (0.63) | RARBPTPN11TP53TSHRPLA2G4B | |
| SCHEMBL9647287 | 0.93 | RARB (0.59) | RARBPTPN11TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302875-B1 | OPTICALLY ACTIVE NAPHTHALENE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN (GB) | 1991-02-27 | — | — | EP | disclosed |