Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | FABP3 | P05413 | 5/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL673756 | 0.93 | CA1 (0.62) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Butyric Acid SCHEMBL487046 | 0.93 | FFAR3 (0.64) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Valeric Acid SCHEMBL19348250 | 0.93 | CA1 (0.70) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Hexanoate SCHEMBL5280114 | 0.91 | CA1 (0.60) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Sebacic Acid SCHEMBL8648840 | 0.91 | CA1 (0.60) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Azelaic Acid SCHEMBL4377214 | 0.91 | CA1 (0.60) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Succinic Acid SCHEMBL10749603 | 0.91 | CA1 (0.54) | CA1FFAR3HDAC3HDAC1HDAC2 | |
| Tridecanoate SCHEMBL5459906 | 0.89 | FABP3 (0.60) | CA1CES2CES1FABP3NFKB1 | |
| Nonanoate SCHEMBL8365974 | 0.89 | FABP3 (0.60) | CA1CES2CES1FABP3NFKB1 | |
| Heptanoate SCHEMBL8361326 | 0.89 | FABP3 (0.60) | CA1CES2CES1FABP3NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4973737-A | ORGANOTIN OR ORGANOTITANATE CATALYST, BY-PRODUCT INHIBITION | KABUSHIKI KAISHA VENO SEIYAKU OYO KENKYUO (JP) | 1990-11-27 | — | — | US | claimed |
| US-11885456-B2 | Tape for insulation jacket and method of insulating an object | AVERY DENNISON CORPORATION (US) | 2024-01-30 | — | — | US | disclosed |
| US-11852275-B2 | Tape for insulation jacketing and method of forming securable insulation jacket | AVERY DENNISON CORPORATION (US) | 2023-12-26 | — | — | US | disclosed |
| US-11725068-B2 | Cyclic polyolefins derived from hexyne, octyne, nonyne, pentadecyne and their copolymers with acetylene | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-08-15 | — | — | US | disclosed |
| US-11541639-B2 | Low outgassing clean adhesive | AVERY DENNISON CORPORATION (US) | 2023-01-03 | — | — | US | disclosed |
| CN-111163938-B | Low-outgassing cleaning adhesive | 艾利丹尼森公司 | 2022-09-09 | — | — | CN | disclosed |
| US-20220025082-A1 | CYCLIC POLYOLEFINS DERIVED FROM HEXYNE, OCTYNE, NONYNE, PENTADECYNE AND THEIR COPOLYMERS WITH ACETYLENE | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. | 2022-01-27 | — | — | US | disclosed |
| US-11155653-B2 | Cyclic polyolefins derived from hexyne, octyne, nonyne, pentadecyne and their copolymers with acetylene | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2021-10-26 | — | — | US | disclosed |
| US-20210301968-A1 | Tapes for Insulation Jacketing | AVERY DENNISON CORPORATION | 2021-09-30 | — | — | US | disclosed |
| US-20210293369-A1 | Tapes for Insulation Jacketing | AVERY DENNISON CORPORATION | 2021-09-23 | — | — | US | disclosed |
| WO-1996025901-A1 | MOTTLE PREVENTION FILM OR COATING | AVERY DENNISON CORPORATION (US) | 1996-08-29 | — | — | WO | disclosed |
| US-4973737-A | ORGANOTIN OR ORGANOTITANATE CATALYST, BY-PRODUCT INHIBITION | KABUSHIKI KAISHA VENO SEIYAKU OYO KENKYUO (JP) | 1990-11-27 | — | — | US | disclosed |
| US-4822838-A | BLENDED WITH EPICHLORHYDRIN POLYMER OR POLYMERS | OSAKA SODA CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| EP-0117502-B1 | PROCESS FOR PRODUCING BENZYL ESTERS OF AROMATIC HYDROXYCARBOXYLIC ACIDS | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1987-11-19 | — | — | EP | disclosed |
| US-4624900-A | Aqueous polysiloxane emulsions for anti-adhesive/water-repellent coatings | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1986-11-25 | — | — | US | disclosed |
| EP-0117502-A1 | Process for producing benzyl esters of aromatic hydroxycarboxylic acids | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) | 1984-09-05 | — | — | EP | disclosed |
| US-4281076-A | CURING AT LOW TEMPERATURE, COMPRISING A DIBASIC ACID, A BLOCKED ISOCYANATE AND A TIN COMPOUND | KANSAI PAINT COMPANY, LIMITED (JP) | 1981-07-28 | — | — | US | disclosed |
| US-4064096-A | Curable, storage-stable liquid organopolysiloxane compositions | RHONE-POULENC INDUSTRIES (FR) | 1977-12-20 | — | — | US | disclosed |
| US-4018734-A | Organosilicon compositions which impart non-stick properties to cellulosic and synthetic materials | RHONE-POULENC INDUSTRIES (FR) | 1977-04-19 | — | — | US | disclosed |
| US-3936578-A | Method of rendering a substrate non-stick towards tacky substances by coating the substrate with an organosilicon composition | RHONE-POULENC S.A. (FR) | 1976-02-03 | — | — | US | disclosed |