Adipic Acid

Adipic Acid

SCHEMBL673756

CCCC[Sn+2]CCCC.O=C([O-])CCCCC(=O)[O-]

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC18A2SLC6A2SLC6A3

The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.62
FABP3 P05413 7/20 0.53
FFAR3 O14843 2/20 0.50
HDAC3 O15379 2/20 0.50
HDAC1 Q13547 2/20 0.50
HDAC2 Q92769 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
CES2 O00748 3/20 0.48
CES1 P23141 3/20 0.48
NFKB1 P19838 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sebacic Acid SCHEMBL8648840 0.98 CA1 (0.60) CA1FABP3FFAR3HDAC3HDAC1
Hexanoate SCHEMBL5280114 0.98 CA1 (0.60) CA1FABP3FFAR3HDAC3HDAC1
Azelaic Acid SCHEMBL4377214 0.98 CA1 (0.60) CA1FABP3FFAR3HDAC3HDAC1
Dodecanoate SCHEMBL4869587 0.96 FABP3 (0.60) CA1FABP3CES2CES1NFKB1
Dodecanoate SCHEMBL35315 0.96 FABP3 (0.60) CA1FABP3CES2CES1NFKB1
Tridecanoate SCHEMBL5459906 0.96 FABP3 (0.60) CA1FABP3CES2CES1NFKB1
Heptanoate SCHEMBL8361326 0.96 FABP3 (0.60) CA1FABP3CES2CES1NFKB1
Palmitic Acid SCHEMBL2452648 0.96 FABP3 (0.60) CA1FABP3CES2CES1NFKB1
Nonanoate SCHEMBL8365974 0.96 FABP3 (0.60) CA1FABP3CES2CES1NFKB1
Myristic Acid SCHEMBL9245302 0.96 FABP3 (0.60) CA1FABP3CES2CES1NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11926708-B1 Fluorosilicone compositions and methods related thereto NUSIL TECHNOLOGY LLC (US) 2024-03-12 US claimed
CN-115160536-B High-voltage cable terminal sealing method 国网上海市电力公司 2023-09-12 CN claimed
CN-115160536-A High-voltage cable terminal sealing method 国网上海市电力公司 2022-10-11 CN claimed
US-4973737-A ORGANOTIN OR ORGANOTITANATE CATALYST, BY-PRODUCT INHIBITION KABUSHIKI KAISHA VENO SEIYAKU OYO KENKYUO (JP) 1990-11-27 US claimed
WO-1987005037-A1 ROOM TEMPERATURE VULCANIZABLE ORGANOPOLYSILOXANE COMPOSITIONS AND METHOD FOR MAKING GENERAL ELECTRIC COMPANY (US) 1987-08-27 WO claimed
US-4461867-A CONTAINING A DIORGANOCYCLOPOLYSILOXANE COMPOUND GENERAL ELECTRIC COMPANY (US) 1984-07-24 US claimed
EP-0000879-A1 Process for the preparation of aromatic carbonic acid esters BAYER AG (DE) 1979-03-07 EP claimed
US-12460065-B2 Thermal interface materials based on two-part polyurethanes HENKEL AG & CO. KGAA (DE) 2025-11-04 US disclosed
US-12269059-B2 Silicone compositions and methods related thereto NUSIL TECHNOLOGY LLC (US) 2025-04-08 US disclosed
US-11926708-B1 Fluorosilicone compositions and methods related thereto NUSIL TECHNOLOGY LLC (US) 2024-03-12 US disclosed
CN-113646351-B Thermal interface material based on two-part polyurethane 汉高股份有限及两合公司 2023-11-21 CN disclosed
CN-115160536-B High-voltage cable terminal sealing method 国网上海市电力公司 2023-09-12 CN disclosed
EP-3456746-B1 TERMINAL-MODIFIED CONJUGATED DIENE-BASED POLYMER, RUBBER COMPOSITION, AND RUBBER ARTICLE BRIDGESTONE CORP (JP) 2023-04-19 EP disclosed
EP-0000880-B1 PROCESS FOR THE PREPARATION OF AROMATIC CARBONIC ACID ESTERS BAYER AG (DE) 1981-01-14 EP disclosed
US-4191587-A TREATING WITH AN ORGANOSILICON COMPOUND AND A TIN COMPOUND WACKER-CHEMIE GMBH (DE) 1980-03-04 US disclosed
EP-0000879-A1 Process for the preparation of aromatic carbonic acid esters BAYER AG (DE) 1979-03-07 EP disclosed
EP-0000880-A1 Process for the preparation of aromatic carbonic acid esters BAYER AG (DE) 1979-03-07 EP disclosed
US-4077822-A Splice for use during the thermal stabilization of a flat multifilament band of an acrylic fibrous material comprising at least two segments CELANESE CORPORATION (US) 1978-03-07 US disclosed
US-4036813-A TRIORGANOSILYL-ORGANO-CARBAMATES OR -ALLOPHANATES GENERAL ELECTRIC COMPANY (US) 1977-07-19 US disclosed
US-3962160-A NOVEL ORGANOFUNCTIONAL (KETOXIMINO) SILANES AND ROOM TEMPERATURE, VULCANIZABLE COMPOSITIONS CONTAINING THE SAME GENERAL ELECTRIC COMPANY (US) 1976-06-08 US disclosed