SCHEMBL3977992

SCHEMBL3977992

Oc1ccc(-c2cnc(-c3ccc(O)cc3)cn2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.57
MAPK1 P28482 1/20 0.55
RIPK1 Q13546 1/20 0.55
MAPT P10636 4/20 0.54
ALDH1A1 P00352 2/20 0.54
HPGD P15428 2/20 0.54
HSD17B10 Q99714 2/20 0.54
POLB P06746 1/20 0.54
HSD17B1 P14061 1/20 0.54
HSD17B2 P37059 1/20 0.54
ESR1 P03372 2/20 0.53
ESR2 Q92731 1/20 0.53
NPC1 O15118 4/20 0.52
RAB9A P51151 4/20 0.52
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
AKR1B1 P15121 1/20 0.50
KDM1A O60341 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
NFKB1 P19838 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9446910 0.87 BCHE (0.47) BCHEMAPK1RIPK1MAPTALDH1A1
SCHEMBL10615865 0.87 BCHE (0.47) BCHEMAPK1RIPK1MAPTALDH1A1
SCHEMBL6700757 0.87 PIK3CG (0.47) BCHEMAPK1RIPK1MAPTALDH1A1
SCHEMBL1491731 0.82 NPC1 (0.58) BCHEMAPK1RIPK1MAPTALDH1A1
Phenol SCHEMBL27328542 0.82 HSD17B1 (0.65) BCHEMAPK1HSD17B1HSD17B2MEN1
SCHEMBL7277326 0.82 MMP3 (0.44) BCHEMAPK1RIPK1MAPTALDH1A1
SCHEMBL2645237 0.79 CYP2D6 (0.51) BCHEMAPK1RIPK1MAPTALDH1A1
SCHEMBL23632228 0.77 KDM1A (0.49) BCHEMAPK1RIPK1MAPTALDH1A1
SCHEMBL12970413 0.77 CCR1 (0.60) BCHEMAPTALDH1A1HPGDHSD17B10
SCHEMBL12987394 0.77 NPC1 (0.53) BCHEMAPTALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5746949-A Polarizer films comprising aromatic liquid crystalline polymers comprising dichroic dyes in their main chains HOECHST CELANESE CORP. (US) 1998-05-05 US claimed
JP-62104835-A None JP disclosed
JP-2138267-A None JP disclosed
JP-2149568-A None JP disclosed
CN-101062975-B Aromatic polycarbonate resin, process for producing the same, molding material for optical parts, and optical parts IDEMITSU KOSAN CO 2012-05-30 CN disclosed
EP-1469026-B1 AROMATIC POLYCARBONATE RESIN PROCESS FOR PRODUCING THE SAME OPTICAL PART MOLDING MATERIAL AND OPTICAL PART IDEMITSU KOSAN CO (JP) 2009-05-06 EP disclosed
US-7329718-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2008-02-12 US disclosed
US-20060270823-A1 Suited to a molding material for an optical disc substrate such as a digital audio disc, a digital video disc and an optical memory disc, various lenses such as a lens for an optical pickup, spectacle lenses, contact lenses and a lens sheet, an optical sheet substrate IDEMITSU KOSAN CO., LTD (JP) 2006-11-30 US disclosed
US-7112644-B2 Aromatic polycarbonate resin, process for producing the same, optical-part molding material, and optical part IDEMITSU KOSAN CO., LTD. (JP) 2006-09-26 US disclosed
EP-1361241-B1 Process for producing raw polycarbonate resin material and producing polycarbonate resin IDEMITSU KOSAN CO (JP) 2005-08-24 EP disclosed
WO-1996012750-A1 POLYMER COMPOSITIONS CONTAINING SUBSTITUTED BIPHENYL PYRAZINES HOECHST CELANESE CORPORATION (US) 1996-05-02 WO disclosed
WO-1996012709-A1 SUBSTITUTED BIPHENYL PYRAZINES HOECHST CELANESE CORPORATION (US) 1996-05-02 WO disclosed
US-5464941-A Polymer blends for paints HOECHST CELANESE CORPORATION (US) 1995-11-07 US disclosed
US-5464923-A Polymer blends for paints HOECHST CELANESE CORPORATION (US) 1995-11-07 US disclosed
US-5459266-A Hydroxyphenyl-substituted as monomers for polyesters, polyaryl ates, polyether ketones, polycarbonates, polyepoxides HOECHST CELANESE CORPORATION (US) 1995-10-17 US disclosed
US-5430123-A Polymer compositions containing substituted pyrazines HOECHST CELANESE CORPORATION (US) 1995-07-04 US disclosed
US-5393860-A Functional monomers for high performance polymers HOECHST CELANESE CORPORATION (US) 1995-02-28 US disclosed
JP-H02149568-A OPTICALLY ACTIVE PYRAZINE COMPOUND AND LIQUID CRYSTAL COMPOSITION AJINOMOTO CO INC 1990-06-08 JP disclosed
JP-H02138267-A PYRAZINE COMPOUND AND LIQUID CRYSTAL COMPOSITION AJINOMOTO CO INC 1990-05-28 JP disclosed
JP-S62104835-A POLYCARBONATE HAVING PYRAZINE RING AND ITS PRODUCTION IDEMITSU PETROCHEM CO LTD 1987-05-15 JP disclosed