SCHEMBL3978151

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1114945	0.89	RAB9A (0.56)	RAB9ANPC1POLBKDM4EMAPT
	SCHEMBL3979949	0.86	RAB9A (0.52)	RAB9ANPC1POLBKDM4EMAPT
	SCHEMBL14068236	0.85	TP53 (0.62)	RAB9ANPC1KDM4EMAPTALDH1A1
	SCHEMBL4984937	0.84	RAB9A (0.50)	RAB9ANPC1POLBKDM4EMAPT
	SCHEMBL13612901	0.83	RAB9A (0.50)	RAB9ANPC1POLBKDM4EMAPT
	SCHEMBL3005279	0.83	CYP1A2 (0.66)	RAB9ANPC1KDM4EMAPTALDH1A1
	SCHEMBL3976578	0.82	NR1I3 (0.48)	RAB9ANPC1POLBKDM4EMAPT
	SCHEMBL3978167	0.82	RAB9A (0.52)	RAB9ANPC1POLBKDM4EMAPT
	SCHEMBL3977427	0.81	RAB9A (0.48)	RAB9ANPC1POLBKDM4EMAPT
	SCHEMBL4980360	0.80	RAB9A (0.48)	RAB9ANPC1POLBKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.