Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13612901 | 0.93 | RAB9A (0.50) | RAB9AKMT2ACYP1A2ADRA2AMAOA | |
| SCHEMBL3005279 | 0.93 | CYP1A2 (0.66) | RAB9AKMT2ACYP1A2ADRA2AMAOA | |
| SCHEMBL3978167 | 0.92 | RAB9A (0.52) | RAB9AKMT2ACYP1A2ADRA2AMAOA | |
| SCHEMBL3977427 | 0.91 | RAB9A (0.48) | RAB9AKMT2ACYP1A2ADRA2AMAOA | |
| SCHEMBL3978151 | 0.89 | RAB9A (0.67) | RAB9AKMT2ACYP1A2ADRA2AMAOA | |
| SCHEMBL3979949 | 0.88 | RAB9A (0.52) | RAB9AKMT2ACYP1A2ADRA2AMAOA | |
| SCHEMBL4984937 | 0.86 | RAB9A (0.50) | RAB9AKMT2ACYP1A2ADRA2AMAOA | |
| SCHEMBL30476642 | 0.86 | NPC1 (0.53) | RAB9AMAPTPOLBALDH1A1GAA | |
| SCHEMBL19996133 | 0.86 | NPC1 (0.53) | RAB9AMAPTPOLBALDH1A1GAA | |
| SCHEMBL30875475 | 0.85 | CA12 (0.49) | RAB9AMAPTALDH1A1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220143201-A1 | COMPOSITION COMPRISING A POLYMERIC REAGENT | NEKTAR THERAPEUTICS (US) | 2022-05-12 | — | — | US | disclosed |
| US-20220143201-A1 | COMPOSITION COMPRISING A POLYMERIC REAGENT | NEKTAR THERAPEUTICS (US) | 2022-05-12 | — | — | US | disclosed |
| US-11266742-B2 | Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates | NEKTAR THERAPEUTICS (US) | 2022-03-08 | — | — | US | disclosed |
| US-20200276320-A1 | COMPOSITION COMPRISING A POLYMERIC REAGENT | NEKTAR THERAPEUTICS (US) | 2020-09-03 | — | — | US | disclosed |
| US-20200276320-A1 | COMPOSITION COMPRISING A POLYMERIC REAGENT | NEKTAR THERAPEUTICS (US) | 2020-09-03 | — | — | US | disclosed |
| US-10695435-B2 | Composition comprising a polymeric reagent | NEKTAR THERAPEUTICS (US) | 2020-06-30 | — | — | US | disclosed |
| US-10695435-B2 | Composition comprising a polymeric reagent | NEKTAR THERAPEUTICS (US) | 2020-06-30 | — | — | US | disclosed |
| US-20190046651-A1 | COMPOSITION COMPRISING A POLYMERIC REAGENT | NEKTAR THERAPEUTICS | 2019-02-14 | — | — | US | disclosed |
| US-20190046651-A1 | COMPOSITION COMPRISING A POLYMERIC REAGENT | NEKTAR THERAPEUTICS | 2019-02-14 | — | — | US | disclosed |
| US-10130720-B2 | Composition comprising a polymeric reagent | NEKTAR THERAPEUTICS (US) | 2018-11-20 | — | — | US | disclosed |
| EP-1968644-B1 | POLYMER CONJUGATES OF GLP-1 | NEKTAR THERAPEUTICS (US) | 2012-06-27 | — | — | EP | disclosed |
| EP-2364735-A2 | Branched PEG conjugates of GLP-1 | Nektar Therapeutics (US) | 2011-09-14 | — | — | EP | disclosed |
| EP-2279758-A2 | Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates | Nektar Therapeutics (US) | 2011-02-02 | — | — | EP | disclosed |
| US-20100210505-A1 | POLYMER CONJUGATES OF GLP-1 | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2010-08-19 | — | — | US | disclosed |
| EP-1968644-A2 | POLYMER CONJUGATES OF GLP-1 | Nektar Therapeutics Al, Corporation (US) | 2008-09-17 | — | — | EP | disclosed |
| CN-101242858-A | Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates | NEKTAR THERAPEUTICS AL CORP (US) | 2008-08-13 | — | — | CN | disclosed |
| EP-1896082-A2 | CONJUGATES HAVING A DEGRADABLE LINKAGE AND POLYMERIC REAGENTS USEFUL IN PREPARING SUCH CONJUGATES | Nektar Therapeutics AL, Corporation (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007075534-A2 | POLYMER CONJUGATES OF GLP-1 | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2006138572-A2 | CONJUGATES HAVING A DEGRADABLE LINKAGE AND POLYMERIC REAGENTS USEFUL IN PREPARING SUCH CONJUGATES | NEKTAR THERAPEUTICS AL, CORPORATION (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060293499-A1 | Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates | NEKTAR THERAPEUTICS | 2006-12-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210505-A1 | POLYMER CONJUGATES OF GLP-1 | GLP1R, GIPR, NGLY1 | RAB9A 1283/4885KMT2A 898/4885CYP1A2 4750/4885 |
| US-20220143201-A1 | COMPOSITION COMPRISING A POLYMERIC REAGENT | CD44, FCGRT, C9 | RAB9A 3754/4885KMT2A 2624/4885CYP1A2 2585/4885 |
| US-20200276320-A1 | COMPOSITION COMPRISING A POLYMERIC REAGENT | CD44, FCGRT, C9 | RAB9A 3754/4885KMT2A 2624/4885CYP1A2 2585/4885 |
| US-10130720-B2 | Composition comprising a polymeric reagent | CD44, FCGRT, C9 | RAB9A 3754/4885KMT2A 2624/4885CYP1A2 2585/4885 |
| US-11266742-B2 | Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates | CD44, DNPEP, SI | RAB9A 3259/4885KMT2A 1747/4885CYP1A2 2812/4885 |
| US-20190046651-A1 | COMPOSITION COMPRISING A POLYMERIC REAGENT | CD44, FCGRT, C9 | RAB9A 3754/4885KMT2A 2624/4885CYP1A2 2585/4885 |
| US-10695435-B2 | Composition comprising a polymeric reagent | CD44, FCGRT, C9 | RAB9A 3754/4885KMT2A 2624/4885CYP1A2 2585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.