Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.51 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1342005 | 0.95 | SMN1; SMN2 (0.61) | CYP17A1SMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL20865536 | 0.90 | CYP17A1 (0.68) | CYP17A1SMN1; SMN2PSMB8HTTMAP4K4 | |
| SCHEMBL20865538 | 0.89 | CYP17A1 (0.59) | CYP17A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL7079625 | 0.86 | RAB9A (0.73) | SMN1; SMN2RAB9ANPC1CYP1A2CYP2D6 | |
| SCHEMBL13055402 | 0.84 | CYP17A1 (0.59) | CYP17A1SMN1; SMN2PSMB8ALDH1A1GAA | |
| SCHEMBL30403272 | 0.84 | KMT2A (0.56) | CYP17A1SMN1; SMN2RAB9ANPC1CYP1A2 | |
| SCHEMBL18570243 | 0.83 | CYP17A1 (0.61) | CYP17A1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL3968632 | 0.83 | CYP17A1 (0.61) | CYP17A1SMN1; SMN2PSMB8TP53ALDH1A1 | |
| SCHEMBL22816953 | 0.83 | EPHX2 (0.59) | CYP17A1PSMB8GAAMAP4K4L3MBTL1 | |
| SCHEMBL29131710 | 0.83 | HPGD (0.59) | CYP17A1SMN1; SMN2RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534894-B2 | Biphenyloxy-acids | WYETH (US) | 2009-05-19 | — | — | US | disclosed |
| EP-1667959-A1 | BIPHENYLOXY-ACIDS | Wyeth (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20060020003-A1 | Biphenyloxy-acids | WYETH (US) | 2006-01-26 | — | — | US | disclosed |
| WO-2005030702-A1 | BIPHENYLOXY-ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060020003-A1 | Biphenyloxy-acids | AHR, ARNT, NR1H4 | CYP17A1 194/4885SMN1; SMN2 4625/4885RAB9A 3094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.