Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 9/20 | 0.33 |
| ▸ | PPARA | Q07869 | 8/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045445 | 0.90 | NOTUM (0.43) | NOTUMHDAC6HSD17B10KDM4EMEN1 | |
| Cuminaldehyde SCHEMBL4262679 | 0.85 | TYR (0.47) | TYRNOTUMHSD17B10KDM4ENPC1 | |
| 2-Naphthaldehyde SCHEMBL4258154 | 0.79 | UTRN (0.40) | NOTUMHDAC6HSD17B10KDM4EMEN1 | |
| SCHEMBL3974213 | 0.78 | NOTUM (0.39) | NOTUMHSD17B10KDM4EMEN1NPC1 | |
| SCHEMBL9910120 | 0.76 | PPARG (0.43) | HSD17B10KDM4ENPC1RAB9APPARG | |
| SCHEMBL1048319 | 0.75 | PPARG (0.47) | NOTUMHSD17B10KDM4ENPC1ALDH1A1 | |
| SCHEMBL1928637 | 0.75 | S1PR1 (0.38) | NOTUMHSD17B10KDM4EMEN1NPC1 | |
| SCHEMBL1051790 | 0.74 | NOTUM (0.45) | NOTUMHSD17B10KDM4EMEN1NPC1 | |
| SCHEMBL4257935 | 0.72 | NOTUM (0.38) | NOTUMKDM4EPPARGPPARAPPARD | |
| SCHEMBL3292160 | 0.71 | IKBKB (0.43) | NOTUMHDAC6HSD17B10KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599453-B1 | 3-METHYL-2- (3- (2-PHENYL-OXAZOL-4-YLMETHOXY)-CYCLOHEXANECARBONYL-AMINO BUTYRIC ACID DERIVATIVES AND RELATED COMPOUNDS AS PPAR MODULATORS FOR THE TREATMENT OF TYPE 2 DIABETES AND ATHEROSCLEROSIS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-05-06 | — | — | EP | disclosed |
| EP-1599452-B1 | 3-(2-PHENYL-OXAZOL-4-YL METHOXY) CYCLOHEXYLMETHOXY ACETIC ACID DERIVATIVES AND RELATED COMPOUNDS USED AS PPAR MODULATORS FOR TREATING TYPE 2 DIABETES AND ARTERIOSCLEROSIS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-06-20 | — | — | EP | disclosed |