Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 7/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9910339 | 0.83 | ESR2 (0.46) | PPARGPPARATARBP2PPARDRAB9A | |
| SCHEMBL18095717 | 0.83 | PPARG (0.46) | PPARGPPARATARBP2PPARDKDM4E | |
| SCHEMBL18095687 | 0.83 | PPARG (0.54) | PPARGPPARATARBP2PPARDKDM4E | |
| SCHEMBL6608776 | 0.82 | PPARG (0.42) | PPARGPPARATARBP2PPARDRAB9A | |
| SCHEMBL6603331 | 0.81 | PPARA (0.47) | PPARGPPARATARBP2PPARDKDM4E | |
| SCHEMBL18103290 | 0.80 | TARBP2 (0.56) | PPARGPPARATARBP2PPARDKDM4E | |
| SCHEMBL4478993 | 0.78 | PPARG (0.44) | PPARGPPARAPPARDKDM4EHSD17B10 | |
| Cuminaldehyde SCHEMBL3978618 | 0.76 | TYR (0.45) | PPARGPPARATARBP2PPARDKDM4E | |
| SCHEMBL4065595 | 0.75 | PPARG (0.44) | PPARGPPARATARBP2PPARDKDM4E | |
| SCHEMBL6607542 | 0.74 | PPARG (0.46) | PPARGPPARATARBP2PPARDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074980-A2 | METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISORDERS AND LIVER DISORDERS USING INDANE ACETIC ACID DERIVATIVES | DARA BIOSCIENCES, INC. (US) | 2012-06-07 | — | — | WO | disclosed |