Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 9/20 | 0.36 |
| ▸ | PPARD | Q03181 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 9/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | UTRN | P46939 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3982662 | 0.91 | LMNA (0.42) | NOTUMIKBKBPPARGPPARDLMNA | |
| SCHEMBL4255119 | 0.82 | ALDH1A1 (0.45) | NOTUMPPARGLMNAPPARAUTRN | |
| SCHEMBL13635363 | 0.82 | PPARD (0.39) | NOTUMIKBKBPPARGPPARDLMNA | |
| SCHEMBL3297717 | 0.79 | PPARG (0.47) | NOTUMIKBKBPPARGPPARDLMNA | |
| SCHEMBL18003565 | 0.78 | IKBKB (0.43) | NOTUMIKBKBPPARGPPARDLMNA | |
| SCHEMBL18003198 | 0.78 | IKBKB (0.43) | NOTUMIKBKBPPARGPPARDLMNA | |
| SCHEMBL3977952 | 0.77 | NOTUM (0.38) | NOTUMPPARGPPARDLMNAPPARA | |
| SCHEMBL3293957 | 0.76 | ALDH1A1 (0.49) | NOTUMPPARGLMNAPPARAUTRN | |
| SCHEMBL1050172 | 0.75 | NPC1 (0.41) | NOTUMIKBKBLMNAKDM4EL3MBTL1 | |
| SCHEMBL9260216 | 0.74 | PPARG (0.53) | PPARGPPARDPPARAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599453-B1 | 3-METHYL-2- (3- (2-PHENYL-OXAZOL-4-YLMETHOXY)-CYCLOHEXANECARBONYL-AMINO BUTYRIC ACID DERIVATIVES AND RELATED COMPOUNDS AS PPAR MODULATORS FOR THE TREATMENT OF TYPE 2 DIABETES AND ATHEROSCLEROSIS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-05-06 | — | — | EP | disclosed |
| EP-1599453-A1 | 3-METHYL-2- (3- (2-PHENYL-OXAZOL-4-YLMETHOXY)-CYCLOHEXANECARBONYL-AMINO BUTYRIC ACID DERIVATIVES AND RELATED COMPOUNDS AS PPAR MODULATORS FOR THE TREATMENT OF TYPE 2 DIABETES AND ATHEROSCLEROSIS | Sanofi-Aventis Deutschland GmbH (DE) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004076426-A1 | 3-METHYL-2- (3- (2-PHENYL-OXAZOL-4-YLMETHOXY)-CYCLOHEXANECARBONYL-AMINO BUTYRIC ACID DERIVATIVES AND RELATED COMPOUNDS AS PPAR MODULATORS FOR THE TREATMENT OF TYPE 2 DIABETES AND ATHEROSCLEROSIS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-09-10 | — | — | WO | disclosed |