Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27392332 | 0.79 | POLB (0.49) | POLBCASP6CES2CES1 | |
| SCHEMBL2547829 | 0.68 | POLB (0.69) | POLBCASP6AKR1B1 | |
| SCHEMBL4962715 | 0.66 | POLB (0.42) | POLBCASP6 | |
| SCHEMBL21011969 | 0.65 | CA1 (0.40) | POLBCASP6 | |
| SCHEMBL6978317 | 0.65 | L3MBTL1 (0.35) | — | |
| Formaldehyde SCHEMBL27560205 | 0.65 | POLB (0.64) | POLBCASP6AKR1B1 | |
| SCHEMBL10390650 | 0.62 | POLB (0.50) | POLBCASP6 | |
| SCHEMBL9327125 | 0.59 | POLB (0.56) | POLBCASP6 | |
| Oxalic Acid SCHEMBL28378762 | 0.58 | CES2 (0.54) | CES2CES1 | |
| SCHEMBL10911498 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116730995-B | Hydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-116730995-A | Hydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-114933511-B | Method for quickly converting carboxyl into aldehyde group | 中国科学院兰州化学物理研究所 | 2023-02-24 | — | — | CN | disclosed |
| CN-114933511-A | Method for quickly converting carboxyl into aldehyde group | 中国科学院兰州化学物理研究所 | 2022-08-23 | — | — | CN | disclosed |
| EP-2018371-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007136703-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | WO | disclosed |