Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31297347 | 1.00 | TSHR (0.60) | TSHRCYP3A4MAPK1TDP1HSD11B1 | |
| SCHEMBL4474477 | 0.86 | CYP3A4 (0.43) | TSHRCYP3A4MAPK1TDP1HSD11B1 | |
| SCHEMBL29435960 | 0.81 | HSD11B1 (0.44) | TSHRCYP3A4MAPK1TDP1HSD11B1 | |
| SCHEMBL18167293 | 0.81 | TSHR (0.43) | TSHRCYP3A4MAPK1TDP1HSD11B1 | |
| SCHEMBL364144 | 0.81 | HSD11B1 (0.44) | TSHRCYP3A4MAPK1TDP1HSD11B1 | |
| SCHEMBL803026 | 0.79 | PTGS1 (0.39) | TSHRCYP3A4MAPK1TDP1HSD11B1 | |
| SCHEMBL4460449 | 0.79 | CYP19A1 (0.39) | TSHRCYP3A4MAPK1TDP1HSD11B1 | |
| SCHEMBL11550172 | 0.78 | ALDH1A1 (0.42) | TSHRCYP3A4MAPK1TDP1ALDH1A1 | |
| SCHEMBL31433155 | 0.78 | ALDH1A1 (0.42) | TSHRCYP3A4MAPK1TDP1ALDH1A1 | |
| SCHEMBL17186783 | 0.76 | MEN1 (0.39) | TSHRCYP3A4MAPK1TDP1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306610-A | Synthesis method of 2-chloro-4-fluoro-5-nitrobenzoic acid | 永农生物科学有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-119285433-A | 2-Chloro-4-fluorotrichlorotoluene and preparation method thereof | 鹤壁市宝瑞德化工有限公司 | 2025-01-10 | — | — | CN | claimed |
| CN-114790134-A | Method for synthesizing 2-chloro-4-fluorobenzoic acid through Meerwein arylation reaction | 江苏中旗科技股份有限公司 | 2022-07-26 | — | — | CN | claimed |
| CN-113416114-A | Method for preparing 2-chloro-4-fluoro-trichlorotoluene by catalyzing photochlorination of 2-chloro-4-fluorotoluene through supported phosphorus trichloride | 浙江解氏新材料股份有限公司 | 2021-09-21 | — | — | CN | claimed |
| WO-2018141642-A1 | PROCESS FOR THE PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOTRICHLORIDE | BASF Agro B.V. (NL) | 2018-08-09 | — | — | WO | claimed |
| EP-1853548-B1 | PROCESS FOR THE PREPARATION OF BENZOIC ACID DERIVATIVES VIA A NEW INTERMEDIATE OF SYNTHESIS | MITENI SPA (IT) | 2009-05-13 | — | — | EP | claimed |
| EP-1853548-A1 | PROCESS FOR THE PREPARATION OF BENZOIC ACID DERIVATIVES VIA A NEW INTERMEDIATE OF SYNTHESIS | MITENI S.p.A. (IT) | 2007-11-14 | — | — | EP | claimed |
| WO-2006090210-A1 | PROCESS FOR THE PREPARATION OF BENZOIC ACID DERIVATIVES VIA A NEW INTERMEDIATE OF SYNTHESIS | MITENI S.P.A. (IT) | 2006-08-31 | — | — | WO | claimed |
| US-4163753-A | FROM AN ALIPHATIC ACID ANHYDRIDE AND A TRICHLOROMETHYL AROMATIC COMPOUND | Diaz Chemical Corporation (US) | 1979-08-07 | — | — | US | claimed |
| CN-119306610-A | Synthesis method of 2-chloro-4-fluoro-5-nitrobenzoic acid | 永农生物科学有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119306610-A | Synthesis method of 2-chloro-4-fluoro-5-nitrobenzoic acid | 永农生物科学有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-119285433-A | 2-Chloro-4-fluorotrichlorotoluene and preparation method thereof | 鹤壁市宝瑞德化工有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119285433-A | 2-Chloro-4-fluorotrichlorotoluene and preparation method thereof | 鹤壁市宝瑞德化工有限公司 | 2025-01-10 | — | — | CN | disclosed |
| CN-119143607-A | Saflufenacil intermediate continuous production method of body | 苏利(宁夏)新材料科技有限公司 | 2024-12-17 | — | — | CN | disclosed |
| WO-2006090210-A1 | PROCESS FOR THE PREPARATION OF BENZOIC ACID DERIVATIVES VIA A NEW INTERMEDIATE OF SYNTHESIS | MITENI S.P.A. (IT) | 2006-08-31 | — | — | WO | disclosed |
| WO-2006090210-A1 | PROCESS FOR THE PREPARATION OF BENZOIC ACID DERIVATIVES VIA A NEW INTERMEDIATE OF SYNTHESIS | MITENI S.P.A. (IT) | 2006-08-31 | — | — | WO | disclosed |
| US-4711905-A | 2,4-dihalogenobenzoyl-(thio)urea insecticides | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-08 | — | — | US | disclosed |
| EP-0093976-B1 | 2,4-DIHALOGENBENZOYL UREAS AND THIOUREAS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1986-09-10 | — | — | EP | disclosed |
| EP-0093976-A1 | 2,4-Dihalogenbenzoyl ureas and thioureas, processes for their preparation and their use as pesticides | BAYER AG (DE) | 1983-11-16 | — | — | EP | disclosed |
| US-4163753-A | FROM AN ALIPHATIC ACID ANHYDRIDE AND A TRICHLOROMETHYL AROMATIC COMPOUND | Diaz Chemical Corporation (US) | 1979-08-07 | — | — | US | disclosed |