Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3977832 | 0.98 | NOS2 (0.37) | NOS2LMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3983126 | 0.76 | MEN1 (0.37) | NOS2LMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7665388 | 0.71 | NOS2 (0.31) | NOS2 | |
| SCHEMBL25280113 | 0.68 | MEN1 (0.35) | LMNAALDH1A1SMN1; SMN2MEN1ALOX12 | |
| SCHEMBL3980205 | 0.67 | NOS2 (0.34) | NOS2LMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL16301147 | 0.66 | SSTR4 (0.33) | ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL3984204 | 0.66 | NOS2 (0.33) | NOS2LMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3064939 | 0.65 | NOS2 (0.42) | NOS2LMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3990011 | 0.63 | NOS2 (0.31) | NOS2LMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1237553 | 0.62 | NOS2 (0.39) | NOS2LMNAALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026754-A2 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | Henkel AG & Co. KGaA (DE) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007137676-A2 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | HENKEL AG & CO. KGAA (DE) | 2007-12-06 | — | — | WO | disclosed |