Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978855 | 0.71 | NOS2 (0.39) | NOS2 | |
| SCHEMBL6589864 | 0.70 | — | — | |
| SCHEMBL3977832 | 0.70 | NOS2 (0.37) | NOS2 | |
| SCHEMBL3983126 | 0.67 | MEN1 (0.37) | NOS2 | |
| SCHEMBL6916615 | 0.66 | MEN1 (0.30) | — | |
| SCHEMBL25280113 | 0.63 | MEN1 (0.35) | — | |
| SCHEMBL3980205 | 0.63 | NOS2 (0.34) | NOS2 | |
| SCHEMBL7563664 | 0.62 | — | — | |
| SCHEMBL3984204 | 0.62 | NOS2 (0.33) | NOS2 | |
| SCHEMBL3990011 | 0.59 | NOS2 (0.31) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492406-B1 | PROTEIN KINASE C INHIBITORS; ANTIINFLAMMATORY AND IMMUNO-SUPPRESSIVE AGENTS | ASTRAZENECA AB (SE) | 2002-12-10 | — | — | US | disclosed |