Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980503 | 0.86 | HTT (0.58) | ALDH1A1HTTL3MBTL1KMT2AMAPT | |
| SCHEMBL3988542 | 0.84 | MEN1 (0.56) | ALDH1A1HTTKMT2AMAPTMEN1 | |
| SCHEMBL3983415 | 0.82 | MEN1 (0.60) | ALDH1A1HTTKMT2AMAPTMEN1 | |
| SCHEMBL3990362 | 0.80 | PKM (0.66) | ALDH1A1HTTGAAKMT2AMAPT | |
| SCHEMBL3979152 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HTTGAAL3MBTL1THRB | |
| SCHEMBL29664585 | 0.79 | ALDH1A1 (0.66) | ALDH1A1HTTGAAL3MBTL1THRB | |
| SCHEMBL3124112 | 0.79 | ALDH1A1 (0.66) | ALDH1A1HTTGAAL3MBTL1THRB | |
| SCHEMBL2852168 | 0.77 | KMT2A (0.69) | ALDH1A1HTTGAAL3MBTL1THRB | |
| SCHEMBL2852173 | 0.77 | KMT2A (0.69) | ALDH1A1HTTGAAL3MBTL1THRB | |
| SCHEMBL2312483 | 0.76 | HTT (0.65) | ALDH1A1HTTGAAL3MBTL1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059511-A1 | SULPHOXIMIDES AS PROTEIN KINASE INHIBITORS | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008025556-A1 | SULPHOXIMIDES AS PROTEIN KINASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-06 | — | — | WO | disclosed |