Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | STS | P08842 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.47 |
| ▸ | VEGFA | P15692 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL653520 | 0.93 | HTT (0.54) | KDM4EPKMNPSR1HTTSMN1; SMN2 | |
| SCHEMBL653519 | 0.93 | HTT (0.54) | KDM4EPKMNPSR1HTTSMN1; SMN2 | |
| SCHEMBL18129120 | 0.88 | KDM4E (0.57) | KDM4EPKMSTSMEN1KMT2A | |
| SCHEMBL7985552 | 0.88 | KDM4E (0.69) | KDM4EPKMSMN1; SMN2STSCXCR4 | |
| SCHEMBL13930883 | 0.87 | NPC1 (0.59) | KDM4EPKMNPSR1HTTSMN1; SMN2 | |
| SCHEMBL8350723 | 0.86 | KDM4E (0.64) | KDM4EPKMSTSGPR119TGFBR1 | |
| Hydrochloric Acid SCHEMBL1856109 | 0.85 | TGFBR1 (0.57) | KDM4EPKMSMN1; SMN2STSMEN1 | |
| SCHEMBL3155704 | 0.85 | STS (0.56) | KDM4EPKMNPSR1HTTSMN1; SMN2 | |
| SCHEMBL652849 | 0.84 | HTT (0.57) | KDM4ENPSR1HTTSMN1; SMN2STS | |
| SCHEMBL3083337 | 0.84 | KDM4E (0.58) | KDM4EPKMHTTSTSMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517991-B2 | N-sulfonylpiperidine cannabinoid receptor 1 antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-04-14 | — | — | US | disclosed |
| EP-1814550-A2 | N-SULFONYLPIPERIDINE CANNABINOID RECEPTOR 1 ANTAGONISTS | Bristol-Myers Squibb Company (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006044362-A2 | N-SULFONYLPIPERIDINE CANNABINOID RECEPTOR 1 ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-04-27 | — | — | WO | disclosed |
| US-20060079556-A1 | N-sulfonylpiperidine cannabinoid receptor 1 antagonists | BRISTOL-MYERS SQUIBB COMPANY | 2006-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060079556-A1 | N-sulfonylpiperidine cannabinoid receptor 1 antagonists | CNR1, CNR2, NPY1R | KDM4E 2122/4885PKM 3378/4885NPSR1 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.